Drug: Naldemedine: chronic pain clinical trials
Registry records that list "Drug: Naldemedine" as an intervention. Being studied does not mean an intervention works or is approved.
1
Trials with Canadian sites
0
Recruiting in Canada
6
Registry records in total
Trials in Canada
1 trial, 0 recruiting or not yet recruiting. Recruiting first.
| Phase | Provinces | ||||
|---|---|---|---|---|---|
| Long Term Safety of Naldemedine NCT01965652 | Completed | Phase 3 | Shionogi | 2013-09-24 |
Trials worldwide (outside Canada)
5 trials, 1 recruiting or not yet recruiting. Recruiting first.
| Phase | Countries | ||||
|---|---|---|---|---|---|
| Risk of Major Adverse Cardiovascular Events for Naldemedine & Other Medications for Opioid Induced Constipation NCT03720613 | Recruiting | United States | BioDelivery Sciences International | 2019-01-04 | |
| Efficacy and Safety of Naldemedine in Treating Opioid-induced Constipation NCT01993940 | Completed | Phase 3 | United States | Shionogi | 2013-11-04 |
| Efficacy and Safety of Naldemedine in the Treatment of Opioid-induced Constipation NCT01965158 | Completed | Phase 3 | Austria, Czechia, Germany, Poland and 3 more | Shionogi | 2013-08-29 |
| A Study of Naldemedine (S-297995) for the Treatment of Opioid-Induced Constipation in Adults With Non-Malignant Chronic Pain Receiving Opioid Therapy NCT01443403 | Completed | Phase 2 | United States | Shionogi | 2011-08-17 |
| Study to Evaluate the Safety and Efficacy of Naldemedine (S-297995) for the Treatment of Opioid-Induced Bowel Dysfunction in Subjects With Chronic Pain NCT01122030 | Completed | Phase 2 | United States | Shionogi | 2010-05-19 |
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.