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Fibromyalgia: clinical trials and information

Fibromyalgia is a long-term condition described by widespread body pain, often with fatigue, sleep problems and difficulty with memory or concentration. Its causes are not fully understood; research has looked at how the nervous system processes pain signals, and at genetics, infections, physical or emotional trauma and stress as possible contributing factors. It is diagnosed more often in women than in men.
13
Trials with Canadian sites
1
Recruiting in Canada
210
Registry records worldwide

Fibromyalgia clinical trials in Canada

13 trials, recruiting first
PhaseProvinces
Advancing Online Psychology Tools for Chronic Pain
NCT07659873
Not yet recruitingNot applicableOntarioWomen's College Hospital2026-10
Frequency and Impact of Iron Deficiency in Pain Clinic Patients
NCT06665516
CompletedOntarioMcMaster University2025-03-19
Reconsolidation Therapy With Propranolol as a Treatment for Chronic Pain
NCT05085782
CompletedPhase 2QuebecUniversité de Sherbrooke2022-02-07
Safety and Efficacy of Ketamine Intravenous Infusions in the Treatment of Fibromyalgia
NCT06916403
Enrolling by invitationOntarioWilderman Medical Clinic2020-11-30
Effect of CPAP on Symptoms of Patients With Fibromyalgia and Obstructive Sleep Apnea
NCT02717585
WithdrawnNot applicableOntarioWomen's College Hospital2018-12
Complex Chronic Diseases Program Data Registry
NCT03409653
Unknown statusBritish ColumbiaBC Women's Hospital & Health Centre2017-06-12
HBOT in Fibromyalgia
NCT02467218
CompletedNot applicableOntarioUniversity Health Network, Toronto2015-11
The Effectiveness of Operant Learning Versus Energy Conservation Activity Pacing Treatments in Fibromyalgia
NCT01674335
CompletedNot applicableOntarioLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's2012-09
The Impact of Omega-3 Fatty Acid Supplements on Fibromyalgia Symptoms
NCT01352013
CompletedPhase 2QuebecDr. Yoram Shir2012-01
Pain Relief Investigation of Neuromodulation Therapy in an Adult Fibromyalgia Population
NCT00450905
TerminatedPhase 3OntarioFralex Therapeutics2007-03
Nabilone Versus Amitriptyline in Improving Quality of Sleep in Patients With Fibromyalgia
NCT00381199
CompletedNot applicableQuebecMcGill University Health Centre/Research Institute of the McGill University Health Centre2006-04
Qigong vs. Aerobic Exercise in the Treatment of Childhood Chronic Musculoskeletal Pain
NCT00312234
CompletedPhase 2OntarioThe Hospital for Sick Children2005-08
Efficacy and Safety of SR46349B in Patients With Sleep Disorders in Fibromyalgia
NCT00313885
CompletedPhase 2Sanofi2004-04

Fibromyalgia clinical trials worldwide (outside Canada)

197 trials, 39 recruiting or not yet recruiting. Recruiting first.

PhaseCountries
Elucidating the Central Mechanisms of Action for Green Light Therapy in Managing Chronic Pain
NCT05569486
Not yet recruitingNot applicableUnited StatesUniversity of Arizona2026-12-01
Hyperthermia in Patients With Chronic Primary Pain - Effects on Thermoregulation, Somatosensory System and Movement Evoked Pain
NCT07101978
Not yet recruitingNot applicableSwitzerlandBern University of Applied Sciences2026-12-01
Biopsychosocial Risk Influences on the Development and Generation of Early-Onset Chronic Pain
NCT07602595
RecruitingUnited StatesChildren's Hospital Medical Center, Cincinnati2026-10
Empowered Relief for Caregivers
NCT07636980
Not yet recruitingNot applicableUnited StatesStanford University2026-10
Light Bulb Stimuli to Reduce Chronic Pain
NCT07825792
Not yet recruitingNot applicableUnited StatesUniversity of North Carolina, Chapel Hill2026-09-21
Full-Spectrum Cannabis Extract for Chronic Pain and Bone Health Biomarkers in Women
NCT07783295
Not yet recruitingPhase 2BrazilAssociação Pan-Americana Multidisciplinar de Endocanabinologia2026-09-01
Thoracolumbar Fascia Thickness in Women With Fibromyalgia
NCT07839065
RecruitingTurkey (Türkiye)Diskapi Teaching and Research Hospital2026-09-01
Analgesic Efficacy of Multisite rTMS in Fibromyalgia Patients
NCT07642882
RecruitingNot applicableFranceHospital Ambroise Paré Paris2026-09
Prevalence of Fibromyalgia in Patients With Plaque Psoriasis
NCT07773766
Not yet recruitingAssiut University2026-09
PRL2019 in the Treatment of Juvenile Fibromyalgia
NCT07738926
Not yet recruitingNot applicableItalyIstituto Giannina Gaslini2026-08-01
Comparison of Multidimensional Parameters in Women With Fibromyalgia and Healthy Controls
NCT07416097
Not yet recruitingNot applicableTurkey (Türkiye)Izmir Democracy University2026-06-15
Effect of Reflexology on Pain and Sleep Disorders in Females With Fibromyalgia
NCT07614945
RecruitingNot applicableEgyptCairo University2026-06-03
LET for Fibromyalgia
NCT07201818
Not yet recruitingNot applicableUnited StatesUniversity of Texas Southwestern Medical Center2026-06
The Effect of Fermented Grape Juice Consumption on Fibromyalgia Patients
NCT07403929
RecruitingNot applicableTurkey (Türkiye)Hacettepe University2026-03-15
The Effect of Digital Cognitive Behavioural Therapy for Insomnia on Physical Activity in Fibromyalgia
NCT07465991
RecruitingNot applicableUnited KingdomUniversity of Oxford2026-01-01
The Benefits of Natural Medicine, Vitamin IV Therapy and Supplements: Maintaining Good Health Through Nature
NCT05067998
RecruitingUnited StatesFaith A. Richardson2025-12-21
Mindfulness-based Rehabilitation in a University Museum Setting to Reduce Pain and Improve Quality of Life in Women With Fibromyalgia: a Randomized Controlled Trial
NCT07048366
RecruitingNot applicableItalyG. d'Annunzio University2025-11-27
Investigating the Role of Central Pain Hypersensitivity in Skeletal Muscle Neural Drive
NCT07281651
RecruitingUnited KingdomUniversity of Nottingham2025-11-24
Effect of Physical Exercise and Neuromodulation on Pain, Sleep and Fatigue in Patients With Fibromyalgia
NCT07242573
RecruitingNot applicablePolandNational Institute of Geriatrics, Rheumatology and Rehabilitation, Poland2025-11-01
Self-regulation of Real-time fMRI Brain Activity in Chronic Pain
NCT07023523
RecruitingNot applicableUnited StatesBrigham and Women's Hospital2025-10-31
Emotional Allodynia Questionnaire (AEQ) in Fibromyalgia (PEARL)
NCT07677631
RecruitingItalyUniversity of Bari2025-09-10
Modulation of Cortical Brain Activity During Attentional Control
NCT06748976
RecruitingArgentinaNational Council of Scientific and Technical Research, Argentina2025-07-01
Wearable Biofeedback Devices for Remote Physiotherapy and Rehabilitation
NCT06960330
Not yet recruitingNot applicablePakistanUniversity of Karachi2025-05-06
Shiatsu for Chronic Non-Inflammatory Pain in Children and Adolescents
NCT06929598
RecruitingNot applicableIsraelTel Aviv University2025-05-01
Consensus-Based vs. Standardized Physiotherapy for Fibromyalgia
NCT06913868
RecruitingNot applicableEgyptAl Hayah University In Cairo2025-04-21
Yoga Impact in Fibromyalgia, Primary Health Care
NCT06646796
Not yet recruitingNot applicablePortugalUniversity of Coimbra2024-12-01
Relationships of Affect and Neuroinflammation With Clinical Pain in Veterans With Fibromyalgia
NCT06574165
RecruitingNot applicableUnited StatesVA Office of Research and Development2024-11-01
Fibromyalgia Sleep A to ZZZ Study
NCT06567886
RecruitingNot applicableUnited StatesUniversity of Michigan2024-09-27
The Effects of Core Shamanism in Fibromyalgia
NCT06579261
RecruitingNot applicableUnited StatesUniversity of California, Irvine2024-08-01
Biosignature of the Response to Treatment With Cannabis Oil in Individuals With Fibromyalgia
NCT06946940
RecruitingPhase 2IsraelRambam Health Care Campus2024-05-30
The Impact of Psilocybin on Pain in Fibromyalgia Patients
NCT06368492
RecruitingNot applicableNetherlandsMaastricht University2024-05-03
An Algorithm for Approaching Temporomandibular Disorders With Osteopathic Manual Therapy in Patients With Fibromyalgia
NCT06365151
RecruitingNot applicableSpainUniversitat de Lleida2024-04-05
Brief Pain Exposure Therapy (BPET) For Nociplastic Pain
NCT06208514
RecruitingNot applicableUnited StatesUniversity of Michigan2024-03-04
Cognitive Training to Enhance Brain Concordance During Acupuncture
NCT06157866
RecruitingNot applicableUnited StatesSpaulding Rehabilitation Hospital2024-02-16
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
NCT05754190
RecruitingUnited StatesBrown University2023-06-20
Supraspinal Processing of Sensory Aspects of Pain
NCT05814497
RecruitingNot applicableUnited StatesChildren's Hospital Medical Center, Cincinnati2023-05-01
Effects of Breathing and Attention Training (BAT) on Pain Modulation
NCT05773482
RecruitingNot applicableUnited StatesUniversity of Florida2023-04-03
Electroacupuncture Pain Treatment, Mechanical Hyperalgesia, Quality of Life & Expression of Mu+ B Cells in Fibromyalgia
NCT05357157
RecruitingGreeceUniversity of Crete2022-05-31
Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes
NCT05277025
RecruitingUnited StatesUniversity of Florida2022-03-22
Pain & Reward Neuromodulation of CNS Circuits
NCT07525063
Enrolling by invitationNot applicableUnited StatesDuke University2026-07-21
Effectiveness of the Sana Device on Fibromyalgia Symptoms
NCT05394610
WithdrawnNot applicableSana Health2025-12
Validity And Reliability Of The Turkish Version Of The Sex Pain Questionnaire
NCT07536672
Enrolling by invitationTurkey (Türkiye)Kutahya Health Sciences University2025-10-01
Fibromyalgia Syndrome and Chronic Pelvic Pain
NCT07344675
CompletedTurkey (Türkiye)Sisli Hamidiye Etfal Training and Research Hospital2025-07-01
Pain Reprocessing Therapy for Chronic Widespread Pain: a SCED Study
NCT07050758
Active, not recruitingNot applicableNorwayOslo University Hospital2025-05-07
Pain Neuroscience Education, Conditioned Pain Modulation and Emotional Processes in Fibromyalgia
NCT07055971
Enrolling by invitationNot applicableSpainUniversidad de Granada2025-04-09
Experiences and Care Pathways Shared on Social Media Regarding 5 Conditions Causing Chronic Pain
NCT07871578
CompletedFranceCentral Hospital, Nancy, France2025-03-17
Mapping Stress and Pain Interactions (G072323N)
NCT06892977
Enrolling by invitationBelgiumUniversity Ghent2025-02-08
Assessing Central Aspects of Pain
NCT06518278
Active, not recruitingUnited KingdomUniversity of Nottingham2024-10-23
Study of the Influence of POLD Manual Therapy in Fibromyalgia
NCT03939416
WithdrawnNot applicableSpainOmphis Foundation2024-07-01
Evaluation of Work Productivity and Activities of the Fibromyalgia Patients' Relatives
NCT06357793
Unknown statusBaşakşehir Çam & Sakura City Hospital2024-06-15

About Fibromyalgia

What is Fibromyalgia?

Fibromyalgia is a long-term condition described by widespread body pain, often with fatigue, sleep problems and difficulty with memory or concentration. Its causes are not fully understood; research has looked at how the nervous system processes pain signals, and at genetics, infections, physical or emotional trauma and stress as possible contributing factors. It is diagnosed more often in women than in men.

How is Fibromyalgia usually assessed?

There is no single laboratory test for fibromyalgia. Clinicians usually base a diagnosis on a person's history of widespread pain and other symptoms over several months, a physical examination, and tests to rule out other conditions with similar symptoms.

What kinds of treatments are studied for Fibromyalgia?

Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.

How can I find Fibromyalgia clinical trials in Canada?

This page lists 13 registry records for this term with at least one site in Canada, recruiting studies first. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.

Related conditions

Related interventions

Related US FDA drug labels

Labels whose indications text mentions this term. US labels, not Health Canada Product Monographs.

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.