Fibromyalgia: clinical trials and information
Fibromyalgia clinical trials in Canada
| Phase | Provinces | ||||
|---|---|---|---|---|---|
| Advancing Online Psychology Tools for Chronic Pain NCT07659873 | Not yet recruiting | Not applicable | Ontario | Women's College Hospital | 2026-10 |
| Frequency and Impact of Iron Deficiency in Pain Clinic Patients NCT06665516 | Completed | Ontario | McMaster University | 2025-03-19 | |
| Reconsolidation Therapy With Propranolol as a Treatment for Chronic Pain NCT05085782 | Completed | Phase 2 | Quebec | Université de Sherbrooke | 2022-02-07 |
| Safety and Efficacy of Ketamine Intravenous Infusions in the Treatment of Fibromyalgia NCT06916403 | Enrolling by invitation | Ontario | Wilderman Medical Clinic | 2020-11-30 | |
| Effect of CPAP on Symptoms of Patients With Fibromyalgia and Obstructive Sleep Apnea NCT02717585 | Withdrawn | Not applicable | Ontario | Women's College Hospital | 2018-12 |
| Complex Chronic Diseases Program Data Registry NCT03409653 | Unknown status | British Columbia | BC Women's Hospital & Health Centre | 2017-06-12 | |
| HBOT in Fibromyalgia NCT02467218 | Completed | Not applicable | Ontario | University Health Network, Toronto | 2015-11 |
| The Effectiveness of Operant Learning Versus Energy Conservation Activity Pacing Treatments in Fibromyalgia NCT01674335 | Completed | Not applicable | Ontario | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2012-09 |
| The Impact of Omega-3 Fatty Acid Supplements on Fibromyalgia Symptoms NCT01352013 | Completed | Phase 2 | Quebec | Dr. Yoram Shir | 2012-01 |
| Pain Relief Investigation of Neuromodulation Therapy in an Adult Fibromyalgia Population NCT00450905 | Terminated | Phase 3 | Ontario | Fralex Therapeutics | 2007-03 |
| Nabilone Versus Amitriptyline in Improving Quality of Sleep in Patients With Fibromyalgia NCT00381199 | Completed | Not applicable | Quebec | McGill University Health Centre/Research Institute of the McGill University Health Centre | 2006-04 |
| Qigong vs. Aerobic Exercise in the Treatment of Childhood Chronic Musculoskeletal Pain NCT00312234 | Completed | Phase 2 | Ontario | The Hospital for Sick Children | 2005-08 |
| Efficacy and Safety of SR46349B in Patients With Sleep Disorders in Fibromyalgia NCT00313885 | Completed | Phase 2 | Sanofi | 2004-04 |
Fibromyalgia clinical trials worldwide (outside Canada)
197 trials, 39 recruiting or not yet recruiting. Recruiting first.
| Phase | Countries | ||||
|---|---|---|---|---|---|
| Elucidating the Central Mechanisms of Action for Green Light Therapy in Managing Chronic Pain NCT05569486 | Not yet recruiting | Not applicable | United States | University of Arizona | 2026-12-01 |
| Hyperthermia in Patients With Chronic Primary Pain - Effects on Thermoregulation, Somatosensory System and Movement Evoked Pain NCT07101978 | Not yet recruiting | Not applicable | Switzerland | Bern University of Applied Sciences | 2026-12-01 |
| Biopsychosocial Risk Influences on the Development and Generation of Early-Onset Chronic Pain NCT07602595 | Recruiting | United States | Children's Hospital Medical Center, Cincinnati | 2026-10 | |
| Empowered Relief for Caregivers NCT07636980 | Not yet recruiting | Not applicable | United States | Stanford University | 2026-10 |
| Light Bulb Stimuli to Reduce Chronic Pain NCT07825792 | Not yet recruiting | Not applicable | United States | University of North Carolina, Chapel Hill | 2026-09-21 |
| Full-Spectrum Cannabis Extract for Chronic Pain and Bone Health Biomarkers in Women NCT07783295 | Not yet recruiting | Phase 2 | Brazil | Associação Pan-Americana Multidisciplinar de Endocanabinologia | 2026-09-01 |
| Thoracolumbar Fascia Thickness in Women With Fibromyalgia NCT07839065 | Recruiting | Turkey (Türkiye) | Diskapi Teaching and Research Hospital | 2026-09-01 | |
| Analgesic Efficacy of Multisite rTMS in Fibromyalgia Patients NCT07642882 | Recruiting | Not applicable | France | Hospital Ambroise Paré Paris | 2026-09 |
| Prevalence of Fibromyalgia in Patients With Plaque Psoriasis NCT07773766 | Not yet recruiting | Assiut University | 2026-09 | ||
| PRL2019 in the Treatment of Juvenile Fibromyalgia NCT07738926 | Not yet recruiting | Not applicable | Italy | Istituto Giannina Gaslini | 2026-08-01 |
| Comparison of Multidimensional Parameters in Women With Fibromyalgia and Healthy Controls NCT07416097 | Not yet recruiting | Not applicable | Turkey (Türkiye) | Izmir Democracy University | 2026-06-15 |
| Effect of Reflexology on Pain and Sleep Disorders in Females With Fibromyalgia NCT07614945 | Recruiting | Not applicable | Egypt | Cairo University | 2026-06-03 |
| LET for Fibromyalgia NCT07201818 | Not yet recruiting | Not applicable | United States | University of Texas Southwestern Medical Center | 2026-06 |
| The Effect of Fermented Grape Juice Consumption on Fibromyalgia Patients NCT07403929 | Recruiting | Not applicable | Turkey (Türkiye) | Hacettepe University | 2026-03-15 |
| The Effect of Digital Cognitive Behavioural Therapy for Insomnia on Physical Activity in Fibromyalgia NCT07465991 | Recruiting | Not applicable | United Kingdom | University of Oxford | 2026-01-01 |
| The Benefits of Natural Medicine, Vitamin IV Therapy and Supplements: Maintaining Good Health Through Nature NCT05067998 | Recruiting | United States | Faith A. Richardson | 2025-12-21 | |
| Mindfulness-based Rehabilitation in a University Museum Setting to Reduce Pain and Improve Quality of Life in Women With Fibromyalgia: a Randomized Controlled Trial NCT07048366 | Recruiting | Not applicable | Italy | G. d'Annunzio University | 2025-11-27 |
| Investigating the Role of Central Pain Hypersensitivity in Skeletal Muscle Neural Drive NCT07281651 | Recruiting | United Kingdom | University of Nottingham | 2025-11-24 | |
| Effect of Physical Exercise and Neuromodulation on Pain, Sleep and Fatigue in Patients With Fibromyalgia NCT07242573 | Recruiting | Not applicable | Poland | National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland | 2025-11-01 |
| Self-regulation of Real-time fMRI Brain Activity in Chronic Pain NCT07023523 | Recruiting | Not applicable | United States | Brigham and Women's Hospital | 2025-10-31 |
| Emotional Allodynia Questionnaire (AEQ) in Fibromyalgia (PEARL) NCT07677631 | Recruiting | Italy | University of Bari | 2025-09-10 | |
| Modulation of Cortical Brain Activity During Attentional Control NCT06748976 | Recruiting | Argentina | National Council of Scientific and Technical Research, Argentina | 2025-07-01 | |
| Wearable Biofeedback Devices for Remote Physiotherapy and Rehabilitation NCT06960330 | Not yet recruiting | Not applicable | Pakistan | University of Karachi | 2025-05-06 |
| Shiatsu for Chronic Non-Inflammatory Pain in Children and Adolescents NCT06929598 | Recruiting | Not applicable | Israel | Tel Aviv University | 2025-05-01 |
| Consensus-Based vs. Standardized Physiotherapy for Fibromyalgia NCT06913868 | Recruiting | Not applicable | Egypt | Al Hayah University In Cairo | 2025-04-21 |
| Yoga Impact in Fibromyalgia, Primary Health Care NCT06646796 | Not yet recruiting | Not applicable | Portugal | University of Coimbra | 2024-12-01 |
| Relationships of Affect and Neuroinflammation With Clinical Pain in Veterans With Fibromyalgia NCT06574165 | Recruiting | Not applicable | United States | VA Office of Research and Development | 2024-11-01 |
| Fibromyalgia Sleep A to ZZZ Study NCT06567886 | Recruiting | Not applicable | United States | University of Michigan | 2024-09-27 |
| The Effects of Core Shamanism in Fibromyalgia NCT06579261 | Recruiting | Not applicable | United States | University of California, Irvine | 2024-08-01 |
| Biosignature of the Response to Treatment With Cannabis Oil in Individuals With Fibromyalgia NCT06946940 | Recruiting | Phase 2 | Israel | Rambam Health Care Campus | 2024-05-30 |
| The Impact of Psilocybin on Pain in Fibromyalgia Patients NCT06368492 | Recruiting | Not applicable | Netherlands | Maastricht University | 2024-05-03 |
| An Algorithm for Approaching Temporomandibular Disorders With Osteopathic Manual Therapy in Patients With Fibromyalgia NCT06365151 | Recruiting | Not applicable | Spain | Universitat de Lleida | 2024-04-05 |
| Brief Pain Exposure Therapy (BPET) For Nociplastic Pain NCT06208514 | Recruiting | Not applicable | United States | University of Michigan | 2024-03-04 |
| Cognitive Training to Enhance Brain Concordance During Acupuncture NCT06157866 | Recruiting | Not applicable | United States | Spaulding Rehabilitation Hospital | 2024-02-16 |
| Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA NCT05754190 | Recruiting | United States | Brown University | 2023-06-20 | |
| Supraspinal Processing of Sensory Aspects of Pain NCT05814497 | Recruiting | Not applicable | United States | Children's Hospital Medical Center, Cincinnati | 2023-05-01 |
| Effects of Breathing and Attention Training (BAT) on Pain Modulation NCT05773482 | Recruiting | Not applicable | United States | University of Florida | 2023-04-03 |
| Electroacupuncture Pain Treatment, Mechanical Hyperalgesia, Quality of Life & Expression of Mu+ B Cells in Fibromyalgia NCT05357157 | Recruiting | Greece | University of Crete | 2022-05-31 | |
| Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes NCT05277025 | Recruiting | United States | University of Florida | 2022-03-22 | |
| Pain & Reward Neuromodulation of CNS Circuits NCT07525063 | Enrolling by invitation | Not applicable | United States | Duke University | 2026-07-21 |
| Effectiveness of the Sana Device on Fibromyalgia Symptoms NCT05394610 | Withdrawn | Not applicable | Sana Health | 2025-12 | |
| Validity And Reliability Of The Turkish Version Of The Sex Pain Questionnaire NCT07536672 | Enrolling by invitation | Turkey (Türkiye) | Kutahya Health Sciences University | 2025-10-01 | |
| Fibromyalgia Syndrome and Chronic Pelvic Pain NCT07344675 | Completed | Turkey (Türkiye) | Sisli Hamidiye Etfal Training and Research Hospital | 2025-07-01 | |
| Pain Reprocessing Therapy for Chronic Widespread Pain: a SCED Study NCT07050758 | Active, not recruiting | Not applicable | Norway | Oslo University Hospital | 2025-05-07 |
| Pain Neuroscience Education, Conditioned Pain Modulation and Emotional Processes in Fibromyalgia NCT07055971 | Enrolling by invitation | Not applicable | Spain | Universidad de Granada | 2025-04-09 |
| Experiences and Care Pathways Shared on Social Media Regarding 5 Conditions Causing Chronic Pain NCT07871578 | Completed | France | Central Hospital, Nancy, France | 2025-03-17 | |
| Mapping Stress and Pain Interactions (G072323N) NCT06892977 | Enrolling by invitation | Belgium | University Ghent | 2025-02-08 | |
| Assessing Central Aspects of Pain NCT06518278 | Active, not recruiting | United Kingdom | University of Nottingham | 2024-10-23 | |
| Study of the Influence of POLD Manual Therapy in Fibromyalgia NCT03939416 | Withdrawn | Not applicable | Spain | Omphis Foundation | 2024-07-01 |
| Evaluation of Work Productivity and Activities of the Fibromyalgia Patients' Relatives NCT06357793 | Unknown status | Başakşehir Çam & Sakura City Hospital | 2024-06-15 |
About Fibromyalgia
What is Fibromyalgia?
Fibromyalgia is a long-term condition described by widespread body pain, often with fatigue, sleep problems and difficulty with memory or concentration. Its causes are not fully understood; research has looked at how the nervous system processes pain signals, and at genetics, infections, physical or emotional trauma and stress as possible contributing factors. It is diagnosed more often in women than in men.
How is Fibromyalgia usually assessed?
There is no single laboratory test for fibromyalgia. Clinicians usually base a diagnosis on a person's history of widespread pain and other symptoms over several months, a physical examination, and tests to rule out other conditions with similar symptoms.
What kinds of treatments are studied for Fibromyalgia?
Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.
How can I find Fibromyalgia clinical trials in Canada?
This page lists 13 registry records for this term with at least one site in Canada, recruiting studies first. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.
Related conditions
Related interventions
- Drug: placebo (6)
- Behavioral: Treatment as Usual (TAU) (3)
- Behavioral: Education (2)
- Device: rTMS (2)
- Device: transcranial direct current stimulation (2)
- Other: exercise (2)
- Other: Conventional physical therapy (2)
- Other: Control (2)
- Drug: Psilocybin (2)
- Behavioral: Coping Skills Training (1)
- Behavioral: Aerobic exercise (1)
- Device: Repetitive transcranial magnetic stimulation (1)
- Drug: Nabilone (1)
- Device: Sham rTMS (1)
- Drug: lidocaine (1)
- Drug: gabapentin (1)
- Other: Health Education (1)
- Drug: pregabalin (1)
- Behavioral: Tai Chi (1)
- Behavioral: Psychotherapy (1)
Related US FDA drug labels
Labels whose indications text mentions this term. US labels, not Health Canada Product Monographs.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.