Back Pain: clinical trials and information
Chronic low back pain is back pain that lasts for 12 weeks or longer. In many cases no single specific cause is found. It is one of the most common reasons people see a health professional.
7
Trials with Canadian sites
1
Recruiting in Canada
145
Registry records worldwide
Back Pain clinical trials in Canada
7 trials, recruiting first
Back Pain clinical trials worldwide (outside Canada)
138 trials, 9 recruiting or not yet recruiting. Recruiting first.
| Phase | Countries | ||||
|---|---|---|---|---|---|
| Erector Spinae Plane Block Versus Trigger Point Injection for Chronic Thoracic Myofascial Pain NCT07632820 | Recruiting | Phase 4 | United States | Mayo Clinic | 2026-08-13 |
| Hormones, Outcomes, and Pain Pathways in Exercise Study NCT07579182 | Recruiting | Phase 1 | United States | University of Houston | 2026-05-17 |
| Psychological Options for Wellness and Recovery (POWeR) Trial for Veterans With Chronic Back/Neck Pain NCT07137715 | Recruiting | Not applicable | United States | University of Colorado, Denver | 2026-03-27 |
| Safety and Efficacy of Oral Cannabis in Chronic Spine Pain NCT05052541 | Recruiting | Phase 3 | United States | University of Colorado, Denver | 2026-01 |
| Effectiveness of a Multidisciplinary Treatment for Patients With Chronic Low Back Pain NCT06679205 | Recruiting | Not applicable | Spain | University of Barcelona | 2025-01-14 |
| CARES (Comprehensive Analgesic, Recovery, and Education Support) for Surgery Trial NCT06027099 | Recruiting | Phase 3 | United States | Stanford University | 2024-12-05 |
| Haloperidol for Pain Control in Patients With Acute Musculoskeletal Back Pain in the Emergency Department NCT06395428 | Recruiting | Phase 4 | United States | Western Michigan University School of Medicine | 2024-07-09 |
| Brain Mechanisms Supporting Cannabis-induced Pain Relief NCT04982965 | Recruiting | Early phase 1 | United States | University of California, San Diego | 2021-05-07 |
| Impact of Muscle Degeneration in Chronic Low Back Pain NCT04273828 | Recruiting | Brazil | Hospital Israelita Albert Einstein | 2020-04-06 | |
| Diaphragmatic Breathing Exercises and Chronic Non-spesifik Neck and Back Pain NCT07683273 | Enrolling by invitation | Not applicable | Turkey (Türkiye) | Hacettepe University | 2026-06-29 |
| Active Coping: Interdisciplinary Program for Chronic Pain, Physiotherapy Unit (Spain) NCT07504094 | Active, not recruiting | Not applicable | Spain | Universidad de Zaragoza | 2026-04-01 |
| Use of Ultrasound Imaging in Confirming Osteopathic Spinal Diagnosis NCT07858071 | Completed | United States | The Touro College and University System | 2026-03-18 | |
| Effect of Shock Wave Therapy With Core Stability Exercises for Treatment of Chronic Non-Specific Back Pain NCT07319988 | Completed | Not applicable | Egypt, Jordan | New Ismailia National University | 2025-12-01 |
| Workplace Exercise Therapy With or Without Manual Therapy in Chronic Spinal Pain NCT07251959 | Enrolling by invitation | Not applicable | Spain | Catholic University of Murcia | 2025-09-29 |
| Partners4Pain & Wellbeing: A Randomized Trial of Community Supported Complementary and Integrative Health Self-management for Back Pain NCT06696352 | Active, not recruiting | Not applicable | United States | University of Minnesota | 2025-01-06 |
| Development of STEPPT NCT06835439 | Completed | Not applicable | United States | San Diego State University | 2024-11-02 |
| Influence of Verbal Suggestion on the Therapeutic Effect of the Joint Manipulation NCT06537739 | Completed | Not applicable | Poland | John Paul II University in Biała Podlaska | 2024-10-14 |
| Safety and Efficacy of the BTL-043 Device in Alleviating Back Pain NCT07661082 | Completed | Not applicable | United States | BTL Industries Ltd. | 2024-08-09 |
| Changes in Thoracolumbar Fascia Stiffness and Pain Parameters in Young Patients With Chronic Low Back Pain NCT06537219 | Unknown status | Turkey (Türkiye) | Atılım University | 2024-07-15 | |
| Complementary Medicine Practices in Chronic Low Back Pain: Randomized Controlled Trial NCT06407492 | Completed | Not applicable | Turkey (Türkiye) | Uskudar University | 2024-05-09 |
| Feasibility and Acceptability of Group Pain Reprocessing Therapy for Veterans With Chronic Neck/Back Pain NCT06406699 | Completed | Not applicable | United States | University of Colorado, Denver | 2024-04-17 |
| Effectiveness of a Digital Health Application for Subacute and Chronic Back Pain (Relevis) NCT06221956 | Unknown status | Not applicable | Germany | Gaia AG | 2024-01-23 |
| Evaluation of Efficacy and Comfort: A Trial on the Incrediwear Back Brace in Patients With Chronic Lower Back Pain NCT06126887 | Completed | Not applicable | United States | Johns Hopkins University | 2024-01-09 |
| Moderators and Mediators (M & M Trial) of Psychosocial Treatments of Chronic Pain NCT06044649 | Active, not recruiting | Not applicable | United States | Rush University Medical Center | 2023-11-15 |
| Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Back Pain NCT06071962 | Unknown status | Phase 3 | Germany | Apurano Pharmaceuticals GmbH | 2023-11-02 |
| Efficacy and Tolerability of AP707 in Patients With Chronic Back Pain NCT06072560 | Unknown status | Phase 3 | Germany | Apurano Pharmaceuticals GmbH | 2023-11-02 |
| Virtual Reality - A New Vision on Pain NCT06045741 | Completed | Norway | Sykehuset i Vestfold HF | 2023-09-01 | |
| Impact of Scapula Position on Functionality and Balance in People With Chronic Low Back Pain NCT05982964 | Completed | Turkey (Türkiye) | Istanbul Medipol University Hospital | 2023-07-31 | |
| YOga for Patients With Chronic BACK Pain and Poor PROgnosis NCT05953155 | Completed | Not applicable | Brazil | Federal University of Minas Gerais | 2023-07-27 |
| Evaluation of the Sacroiliac Joints of People With Chronic Low Back Pain From a Chiropractic Perspective NCT05821218 | Unknown status | Turkey (Türkiye) | Bahçeşehir University | 2023-04-23 | |
| Acceptability and Efficacy of Pain Reprocessing Therapy in Racially/ Ethnically Diverse Adults With Chronic Back Pain NCT05820204 | Active, not recruiting | Not applicable | United States | Weill Medical College of Cornell University | 2023-04-12 |
| Assessing the Effects of HbA1c Reduction on Alleviating Nonspecific Back Pain NCT06064058 | Completed | Not applicable | Iraq | University of Baghdad | 2023-01-30 |
| Perioperative ACT for Preventing CPSP NCT06750874 | Completed | Not applicable | United States | Samantha Meints | 2023-01-04 |
| X-ray Guided Facet Block in Chronic Low Back Pain NCT05676060 | Unknown status | Assiut University | 2023-01-01 | ||
| Multimodal Intervention in Patients With Non-specific Chronic Low Back Pain: the HEALTHY BACK Project NCT06114264 | Completed | Not applicable | Spain | IBS Granada | 2023-01-01 |
| Testosterone Replacement to Alleviate Pain in Postmenopausal Women (TRAPP Trial) NCT04895306 | Completed | Phase 2 | United States | Brigham and Women's Hospital | 2022-11-15 |
| Sensorial Discrimination in Chronic Low Back Pain NCT05169918 | Completed | Not applicable | Turkey (Türkiye) | Istanbul University - Cerrahpasa | 2022-11-15 |
| Clinical Study for Palliative/Preventive Treatment of Chronic Back Pain NCT05597189 | Completed | Not applicable | Spain | Universidad Católica San Antonio de Murcia | 2022-09-26 |
| Treatment of Chronic Back Pain With Focused Vibroacoustic Stimulation NCT04468516 | Unknown status | Not applicable | Wilfrid Laurier University | 2022-09-01 | |
| Quality Improvement re: Choosing Wisely Back Pain Measures NCT05413070 | Unknown status | United States | Carilion Clinic | 2022-06-15 | |
| Yoga for Chronic Low Back Pain in the Cleveland Clinic Employee Health Plan NCT05319691 | Completed | Not applicable | United States | Robert Saper | 2022-05-03 |
| Vacuum Cupping for Chronic Neck and Back Pain NCT05392283 | Completed | Not applicable | Germany | Jena University Hospital | 2022-05-02 |
| Effects of Cervicothoracic Mobility Program on Low Back Pain NCT05347251 | Completed | Not applicable | Pakistan | Riphah International University | 2022-04-25 |
| Can Patient Expectations Influence Pain Reduction After Epidural Injections in Patients With Low Back Pain? NCT05402631 | Unknown status | Switzerland | Ospedale Regionale di Lugano | 2022-04-20 | |
| BOOST Workshop Versus Traditional 1-1 Physiotherapy for Back Pain NCT04968444 | Unknown status | Not applicable | Guy's and St Thomas' NHS Foundation Trust | 2022-04-01 | |
| Optimizing Mental Health in Orthopedic Care NCT05194722 | Completed | Not applicable | United States | Washington University School of Medicine | 2022-01-06 |
| Effects of Rhythmic Stabilization and Mckenzie Techniques on Non Specific Chronic Low Back Pain NCT05207605 | Completed | Not applicable | Pakistan | Riphah International University | 2021-12-02 |
| A Study of Cybis™ 10:25 THC:CBD Oil in Adults With Chronic Back/Neck Pain NCT04976738 | Completed | Phase 1, Phase 2 | Australia | Cymra Life Sciences | 2021-09-20 |
| The Effectiveness of Thoracal Epidural Steroid and Local Anesthetic Injection NCT06507995 | Completed | Not applicable | Turkey (Türkiye) | Ankara University | 2021-08-15 |
| Hippocampal Stimulation in Chronic Low Back Pain NCT04888494 | Completed | Not applicable | United States | Northwestern University | 2021-06-25 |
About Back Pain
What is Back Pain?
Chronic low back pain is back pain that lasts for 12 weeks or longer. In many cases no single specific cause is found. It is one of the most common reasons people see a health professional.
How is Back Pain usually assessed?
Assessment usually involves a history and physical examination, with attention to warning signs that may need urgent investigation. Imaging is not needed in every case; clinicians decide based on symptoms and findings.
What kinds of treatments are studied for Back Pain?
Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.
How can I find Back Pain clinical trials in Canada?
This page lists 7 registry records for this term with at least one site in Canada, recruiting studies first. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.
Related conditions
- Back Pain Lower Back Chronic59 trials
- Low Back Pain632 trials
- Chronic Low Back Pain384 trials
- Chronic Low-back Pain245 trials
- Chronic Low Back Pain (CLBP)71 trials
- Chronic Low-back Pain (cLBP)36 trials
- Failed Back Surgery Syndrome32 trials
- Lower Back Pain28 trials
- Chronic Back Pain28 trials
- Chronic Non-specific Low Back Pain26 trials
- Low Back Pain, Mechanical26 trials
- Low Back Pain, Recurrent19 trials
Related interventions
- Drug: placebo (8)
- Behavioral: Cognitive behavioral therapy (5)
- Device: Precision Spinal Cord Stimulation System (3)
- Other: placebo (2)
- Other: Control Group (2)
- Other: Control (2)
- Behavioral: Cognitive Functional Therapy (2)
- Behavioral: Cognitive Behavioral Therapy for Chronic Pain (CBT-CP) (2)
- Other: usual care (2)
- Behavioral: Acceptance and Commitment Therapy (2)
- Drug: Adezunap (AP707) (2)
- Drug: Desipramine (1)
- Drug: Buprenorphine transdermal patch (1)
- Drug: Buprenorphine transdermal delivery system (1)
- Device: Precision (1)
- Drug: duloxetine (1)
- Drug: Oxycodone/Naloxone (1)
- Behavioral: Coping Skills Training (1)
- Behavioral: Education (1)
- Drug: Saline (1)
Related US FDA drug labels
Labels whose indications text mentions this term. US labels, not Health Canada Product Monographs.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.