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Low Back Pain: clinical trials and information

Chronic low back pain is back pain that lasts for 12 weeks or longer. In many cases no single specific cause is found. It is one of the most common reasons people see a health professional.
16
Trials with Canadian sites
2
Recruiting in Canada
632
Registry records worldwide

Low Back Pain clinical trials in Canada

16 trials, recruiting first
PhaseProvinces
GLA:D Back Canada - a Program for Chronic and Persistent Low Back Pain
NCT06924671
RecruitingAlbertaUniversity of Alberta2021-06-18
Quebec Low Back Pain Study: Core Dataset
NCT04791891
RecruitingQuebecLaval University2018-11-01
Aging, Mobility and Chronic Low Back Pain
NCT05167877
CompletedOntarioMcMaster University2023-01-15
Ultrasound of the Thoracolumbar Fascia for Diagnosing Chronic Low Back Pain
NCT04843800
TerminatedNot applicableQuebecCentre hospitalier de l'Université de Montréal (CHUM)2022-11-01
Effect of Neuromuscular Electrical Stimulation in Patients With Chronic Low Back Pain
NCT04891692
CompletedNot applicableQuebecConcordia University, Montreal2021-02-22
Effect of a Supervised Exercise Program in Patients With Chronic Low Back Pain
NCT04257253
CompletedNot applicableQuebecConcordia University, Montreal2020-12-01
A Study to Determine the Efficacy and Safety of Fasinumab for the Treatment of Adults With Chronic Low Back Pain
NCT02620020
CompletedPhase 2, Phase 3OntarioRegeneron Pharmaceuticals2016-01-26
A Phase 3 Study of Tanezumab for Chronic Low Back Pain
NCT02528253
CompletedPhase 3Ontario, QuebecPfizer2015-08-18
Walking Away From Back Pain, One Step at a Time
NCT02284958
CompletedNot applicableSaskatchewanUniversity of Saskatchewan2015-04
Prognostic Factors of a Favorable Outcome Following an Exercise Program for Soldiers With Low Back Pain
NCT03464877
CompletedNot applicableQuebecMarc Perron2013-03-19
Clinical and Neuromechanical Predictors for the Evolution of Chronic Non-specific Low Back Pain
NCT02373345
CompletedQuebecUniversité du Québec à Trois-Rivières2013-02
A Dose-ranging Study of the Safety and Effectiveness of JNJ-42160443 as add-on Treatment in Patients With Low Back Pain
NCT00973024
TerminatedPhase 2British Columbia, Newfoundland and Labrador, Ontario, QuebecJohnson & Johnson Pharmaceutical Research & Development, L.L.C.2009-09
Osteopathic Treatment of Low Back Pain
NCT00883987
CompletedNova ScotiaMary Lynch2009-06
Trial of Disc Biacuplasty to Treat Chronic Discogenic Low Back Pain
NCT00749554
TerminatedPhase 4AlbertaBaylis Medical Company2008-04
An Open-label Extension Study With Flexible Dosing of Extended-release (ER) Tapentadol (CG5503) to Treat Patients With Moderate to Severe Chronic Pain
NCT00487435
CompletedPhase 3British Columbia, Newfoundland and Labrador, Ontario, Prince Edward Island, Quebec, SaskatchewanJohnson & Johnson Pharmaceutical Research & Development, L.L.C.2007-06
Study to Demonstrate That Muscle Pattern Recognition (MPR) is an Effective Evaluation Tool for Musculoskeletal Neck or Back Pain
NCT00134225
Unknown statusNot applicableQuebeciTech Medical, Inc.2005-04

Low Back Pain clinical trials worldwide (outside Canada)

616 trials, 70 recruiting or not yet recruiting. Recruiting first.

PhaseCountries
Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal Pain
NCT06987786
Not yet recruitingNot applicableUnited StatesDuke University2026-12-01
TECAR Therapy and Chronic Low Back Pain
NCT07825298
Not yet recruitingNot applicableSaudi ArabiaCairo University2026-10-20
Impact of the Receptive Music Intervention Tool (MUSIC CARE©) on Changes in the Functional Abilities of Patients With Chronic Low Back Pain
NCT07731204
Not yet recruitingNot applicableFranceLNA SANTE2026-10-01
Virtual Tai Chi for Chronic Low Back Pain (Spine 2027)
NCT07772154
Not yet recruitingNot applicableUnited StatesNew York Medical College2026-10-01
Pain Neuroscience Education and Neuromuscular Exercise in Individuals With Chronic Low Back Pain and Central Sensitization
NCT07866690
Not yet recruitingNot applicableTurkey (Türkiye)Izmir Katip Celebi University2026-10
Pain Catastrophizing, Fear of Movement, and Physical Activity in Postmenopausal Women With Chronic Low Back Pain
NCT07856498
RecruitingTurkey (Türkiye)Istanbul Medipol University Hospital2026-09-28
The Association Between Amputation Level and Chronic Low Back Pain After Combat-Related Amputation
NCT07626294
Not yet recruitingUkraineUkrainian Society of Regional Anesthesia and Pain Therapy2026-09-15
Brain Connectivity and Perceptive Surfaces in Chronic Low Back Pain (SUPER-RMNf)
NCT07568353
Not yet recruitingNot applicableItalyG. d'Annunzio University2026-09-01
Spinery Basivertebral Nerve Ablation for Vertebrogenic Chronic Low Back Pain
NCT07696507
Not yet recruitingNot applicableItalyAxon srl2026-09
Core Stability Exercise Among Patients With Chronic Low Back Pain
NCT07842653
Not yet recruitingNot applicableAssiut University2026-09
Biologic Injection For Adults With Lumbar Disc Herniation
NCT07386548
RecruitingNot applicableUnited StatesWeill Medical College of Cornell University2026-08-30
Comparing Yoga Nidra, Yoga, and Control Condition on Pain in Individuals With Chronic Low Back Pain
NCT07543835
RecruitingNot applicableUnited StatesUniversity of Central Florida2026-08-25
Dual-Task Neuromuscular Warm-Up Exercises in Chronic Low Back Pain
NCT07761247
Not yet recruitingNot applicableIstinye University2026-08-25
Acceptance and Commitment Therapy Plus Physiotherapy for Chronic Low Back Pain
NCT07766616
Not yet recruitingNot applicableAl-Azhar University2026-08-20
Device-Based vs Manual Sensory Training in Low Back Pain
NCT07277803
Not yet recruitingNot applicableMedipol University2026-08-15
A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Chronic Low Back Pain
NCT07641504
RecruitingPhase 2Puerto Rico, United StatesEli Lilly and Company2026-08-12
Comparison of Traditional, Synchronous, and Asynchronous Telerehabilitation in Office Workers With Chronic Nonspecific Low Back Pain
NCT07700589
Not yet recruitingNot applicableTurkey (Türkiye)Istanbul Aydın University2026-08-01
Kinetic Control Training Versus Core Stability Exercises on Proprioception and Spatiotemporal Gait Parameters in Chronic Non-specific Low Back Pain
NCT07683676
Not yet recruitingNot applicableCairo University2026-07-10
Sensorimotor Training With a Mobilized Balance Platform in Patients With Chronic Low Back Pain
NCT07603609
RecruitingNot applicableTurkey (Türkiye)Gaziler Physical Medicine and Rehabilitation Education and Research Hospital2026-05-04
Potential of Virtual Reality in Primary Chronic Low Back Pain
NCT07742111
RecruitingNot applicablePortugalAveiro University2026-05-01
High-intensity Laser Therapy and Mulligan Mobilization for Patients With Chronic Nonspecific Low Back Pain
NCT07556926
Not yet recruitingNot applicableJordanAnas Radi Hassan Alashram2026-04-30
How Patient Education Helps Patients With Chronic Musculoskeletal Disorders Stick to Home Exercise for Pain Relief.
NCT07764354
RecruitingNot applicableSaudi ArabiaImam Abdulrahman Bin Faisal University2026-04-12
Evaluation of Stabilization Training With Biofeedback in Lumbosacral Spine Pain Syndrome
NCT07463729
RecruitingNot applicablePolandUniversity of Rzeszow2026-04-01
The Relationship Between Transversus Abdominis Muscle Architecture and Upper Extremity Function in Patients With Chronic Low Back Pain
NCT07474610
RecruitingTurkey (Türkiye)Ilayda Dilan Isik2026-04-01
Comparative Effectiveness Of Exercise, Cognitive Behavioural Therapy, And Their Combination For People With Chronic Musculoskeletal Pain And Poor Sleep: Sleepfit Trial
NCT07532070
RecruitingNot applicableAustralia, United StatesUniversity of Sydney2026-04
The Effects of Eight-Week Baduanjin Exercise on Chronic Low Back Pain and Disability Among Office Workers.
NCT07338045
RecruitingNot applicableChinaUniversiti Sains Malaysia2026-03-15
Chronic Low Back Pain and Osteopathic Manipulation Treatment
NCT07161661
RecruitingNot applicableUnited StatesEdward Hines Jr. VA Hospital2026-03-02
Lumbar and Gluteal Motor Control in Chronic Low Back Pain
NCT07452172
Not yet recruitingNot applicableSpainUniversity of Castilla-La Mancha2026-03-02
Sodium Aescinate for the Treatment of Low Back Pain (LBP) in Adults
NCT07339631
RecruitingPhase 1ChinaXijing Hospital2026-03-01
Assessment of the Evolution of Lumbar Spine Movement Fluidity Using Xsens Inertial Sensors in Subjects With Chronic Low Back Pain Before and After Rehabilitation
NCT07327554
RecruitingNot applicableFranceUniversity Hospital, Montpellier2026-02-23
Post Facilitatiion Stretch and Dry Needling on Hamstring Tightness in Chronic Low Back Pain
NCT07426562
RecruitingNot applicablePakistanRiphah International University2026-02-02
Transcutaneous Electrical Nerve Stimulation (TENS) for the Treatment of Low Back Pain (LBP) in Adults
NCT07368920
RecruitingNot applicableChinaXijing Hospital2026-02-01
Sleep Hygiene Education to Improve Sleep in Chronic Migraine and Back Pain
NCT07425964
Not yet recruitingNot applicableAalborg University2026-02
The Effect of Different Kinesio Taping Techniques Applied to Patients With Chronic Low Back Pain on the Thoracolumbar Fascia
NCT07317518
RecruitingNot applicableTurkey (Türkiye)Kirsehir Ahi Evran Universitesi2026-01-19
Effect of Dry Cupping Therapy Associated With the McKenzie Method in Patients With Chronic Low Back Pain
NCT05459376
Not yet recruitingNot applicableBrazilUniversidade Federal do Rio Grande do Norte2026-01-01
Virtual McKenzie Exercises and Centralization of Pain: A Pilot Study
NCT07285824
Not yet recruitingNot applicableEvidence In Motion2025-12
Assessment of Core Muscles Endurance, Lumber Curvature and Function in Smartphone-addicts With Nonspecific Low Back Pain
NCT07261566
Not yet recruitingEgyptCairo University2025-11-30
Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control
NCT07190807
RecruitingNot applicableUnited StatesBoston Scientific Corporation2025-11-07
ADHERE Trial: Strategies to Improve Mobile App Adherence
NCT07205991
RecruitingNot applicableAustraliaNeuroscience Research Australia2025-10-30
TeleYoga for Chronic Low Back Pain: A Quantitative and Qualitative Study
NCT07216417
RecruitingNot applicableUnited StatesTaylor Rees2025-10-10
Effects of Multifidus Lift Exercise on Endurance, Pain, and Disability in University Students With Low Back Pain
NCT07182825
Not yet recruitingNot applicableTurkey (Türkiye)Mehmet Akif Guler2025-10-01
Measurement of Spinal Kinematics During Various Movements
NCT04334889
Not yet recruitingHaute Ecole de Santé Vaud2025-10
Effects of Global Postural Reeducation on Psychophysical Wellbeing in Housewives With Chronic Non-specific LBP.
NCT07203950
Not yet recruitingNot applicablePakistanRiphah International University2025-09-30
Integrated Healthy Lifestyle and Pain Care for People With Musculoskeletal Conditions Living in Rural Areas.
NCT07173335
RecruitingNot applicableAustraliaUniversity of Sydney2025-09-17
AuriculoTherapy NeuroImaging
NCT06825390
RecruitingNot applicableUnited StatesKeith M Vogt2025-07-30
Activity Management Training in Low Back Pain
NCT07061743
Not yet recruitingNot applicableTurkey (Türkiye)Çankırı Karatekin University2025-07-03
Percussive Therapy vs Instrument-Assisted Soft Tissue Mobilization on Chronic Non-Specific Low Back Pain.
NCT06987162
Not yet recruitingNot applicablePakistanRiphah International University2025-07
Digitally Delivered Treatments to Reduce Chronic Low Back Pain
NCT06984354
RecruitingNot applicableAustraliaNeuroscience Research Australia2025-06-02
Effects of GPR on Non-Specific Chronic Low Back Pain
NCT06928597
RecruitingNot applicableBrazilFederal University of Bahia2025-06-01
Multimodal Imaging and Biospecimen Collection for Low Back Pain (LBPB)
NCT06967363
Not yet recruitingChinaPeking University Third Hospital2025-05-15

About Low Back Pain

What is Low Back Pain?

Chronic low back pain is back pain that lasts for 12 weeks or longer. In many cases no single specific cause is found. It is one of the most common reasons people see a health professional.

How is Low Back Pain usually assessed?

Assessment usually involves a history and physical examination, with attention to warning signs that may need urgent investigation. Imaging is not needed in every case; clinicians decide based on symptoms and findings.

What kinds of treatments are studied for Low Back Pain?

Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.

How can I find Low Back Pain clinical trials in Canada?

This page lists 16 registry records for this term with at least one site in Canada, recruiting studies first. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.

Related conditions

Related interventions

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.