Chronic pain clinical trials in Canada
374 registry records for chronic pain studies with at least one site in Canada. Recruiting status changes often: always confirm on ClinicalTrials.gov.
374 trials, recruiting first
| Phase | Provinces | ||||
|---|---|---|---|---|---|
| The Effect of Preoperative Pelvic Floor Physical Therapy (Prehabilitation) on Postoperative Pain Following Endometriosis Surgery: A Randomized Controlled Trial NCT07827794 | Not yet recruiting | Not applicable | Alberta | University of Alberta | 2027-03-01 |
| The Effect of Chiropractic Care on Opioid Use for Chronic Spinal Pain: A Feasibility Study NCT06160947 | Not yet recruiting | Not applicable | Ontario | McMaster University | 2026-12-01 |
| Transcutaneous Auricular Vagus Nerve Stimulation as a Treatment for Musculoskeletal Pain in Cerebral Palsy NCT07585292 | Not yet recruiting | Not applicable | Ontario | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2026-10-01 |
| Advancing Online Psychology Tools for Chronic Pain NCT07659873 | Not yet recruiting | Not applicable | Ontario | Women's College Hospital | 2026-10 |
| Virtual Reality for Pain and Well-Being in Older Adults NCT07607899 | Recruiting | Not applicable | Quebec | Laval University | 2026-09-14 |
| Co-Adaptation of an Digital Pain Management Program for Canadian Veterans NCT07818980 | Recruiting | Ontario | University Health Network, Toronto | 2026-09-14 | |
| Neurolysis for the Treatment of Medial Chronic Knee Pain Due to Osteoarthritis NCT07178951 | Recruiting | Not applicable | Ontario | FUSMobile Inc. | 2026-09-09 |
| Improving Access to Pelvic Health Physiotherapy for Endometriosis NCT07731776 | Recruiting | Quebec | Université de Sherbrooke | 2026-07-28 | |
| PRT for Chronic Low Back Pain NCT07696741 | Recruiting | Not applicable | Ontario | University Health Network, Toronto | 2026-07-15 |
| Effects of Peripheral Repetitive Peripheral Magnetic Stimulation on Individuals With Elbow or Wrist Chronic Pain NCT07544914 | Recruiting | Not applicable | Manitoba | University of Manitoba | 2026-07-01 |
| Self-Hypnosis Training for Migraine Management (HYlaMI): A Pilot and Proof-of-Concept Study NCT07644299 | Not yet recruiting | Not applicable | Quebec | Ciusss de L'Est de l'Île de Montréal | 2026-06-01 |
| Evaluating the Efficacy and Safety of Octane Aether for Treating Chronic Low Back Pain NCT07614568 | Not yet recruiting | Not applicable | Ontario | Octane Innovation Inc. | 2026-06 |
| Efficacy of Dry Needling in Reducing Pain During Sexual Intercourse NCT07534345 | Recruiting | Not applicable | Quebec | Université de Sherbrooke | 2026-05-11 |
| Dex & Mastectomy Pain NCT07556952 | Recruiting | Phase 4 | Quebec | McGill University Health Centre/Research Institute of the McGill University Health Centre | 2026-04-13 |
| Advanced Brain Imaging-TKA (fMRI-TKA) NCT07464080 | Recruiting | Not applicable | Ontario | Ottawa Hospital Research Institute | 2026-04-01 |
| Ketamine Assisted Psychotherapy for Treating Comorbid Chronic Pain and PTSD NCT07009158 | Recruiting | Phase 1, Phase 2 | Ontario | Dr. Yuliya Knyahnytska | 2026-03-31 |
| Ecstasy to Alleviate SEvere Chronic Neuropathic Pain Trial NCT07301632 | Recruiting | Phase 2 | Ontario | Unity Health Toronto | 2026-01-30 |
| Optimizing the Use of Virtual Reality in Rehabilitation for Individuals With Persistent Shoulder Pain NCT07293312 | Not yet recruiting | Not applicable | Quebec | Laval University | 2026-01-15 |
| Accelerated Neuromodulation for Concurrent Post-Traumatic Stress Disorder (PTSD) & Chronic Pain in Veterans NCT07192536 | Not yet recruiting | Phase 4 | British Columbia | Legion Veterans Village Research Foundation | 2026-01 |
| Does a Virtual Program for Pelvic Pain Improve Pain and Sexual Outcomes in Individuals With Provoked Vestibulodynia? NCT06999395 | Recruiting | Not applicable | Ontario | Queen's University | 2025-12-17 |
| A Study of Pain Reduction After Pulmonary Resection by RATS-TT, RATS-OTC, and Hybrid RATS. NCT07184463 | Recruiting | Quebec | Centre hospitalier de l'Université de Montréal (CHUM) | 2025-12-05 | |
| Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication NCT05585229 | Recruiting | Phase 2 | British Columbia | University of British Columbia | 2025-10-27 |
| Evaluation of a Mind-Body Based Approach for Chronic Pain Treatment NCT07143396 | Not yet recruiting | Not applicable | British Columbia | University of the Fraser Valley | 2025-10 |
| Analgesia Nociception Index In Pediatric Patients With Chronic Pain NCT07145762 | Not yet recruiting | Quebec | McGill University Health Centre/Research Institute of the McGill University Health Centre | 2025-09-15 | |
| Virtual Reality and Cranial Nerve Non-invasive Neuromodulation to Improve Quality of Life for Veterans NCT07137845 | Not yet recruiting | Not applicable | Quebec | Université de Sherbrooke | 2025-09 |
| Virtual Reality and Cranial Nerve Neuromodulation to Manage Chronic Pain NCT07065396 | Not yet recruiting | Not applicable | Quebec | Université de Sherbrooke | 2025-07 |
| Combining Brain Stimulation and Physiotherapy for the Management of Chronic Low Back Pain NCT06999772 | Recruiting | Not applicable | Quebec | Laval University | 2025-06-11 |
| Music as an Adjunct to Ketamine Therapy for Chronic Pain NCT06994559 | Recruiting | Not applicable | Quebec | McGill University | 2025-06-01 |
| Neuroimmune Responses to Exercise in Chronic Back Pain NCT07497425 | Recruiting | Not applicable | Quebec | McGill University | 2025-06-01 |
| Nature-based Intervention for Chronic Pain in Older People NCT07002853 | Recruiting | Not applicable | Quebec | Université du Québec à Chicoutimi | 2025-05-22 |
| Comparison of the Efficacy of an Empowered Relief Single-Session Versus Standard Care for Reducing Postoperative Pain Following Elective Orthopedic Surgery: A Randomized Controlled Trial NCT07392099 | Recruiting | Not applicable | Quebec | Université de Sherbrooke | 2025-05-05 |
| Treatment With Psilocybin for Chronic Neuropathic Pain and Depression (TRANSCEND) NCT06518720 | Recruiting | Phase 2 | Ontario | Centre for Addiction and Mental Health | 2025-04-01 |
| Psilocybin for Enhanced Analgesia in Chronic nEuropathic PAIN NCT06731335 | Recruiting | Phase 2 | Ontario | Unity Health Toronto | 2025-03-05 |
| Randomized Controlled Trial of Custom Foot Orthoses for Chronic Forefoot Pain NCT06962475 | Recruiting | Not applicable | Quebec | Université du Québec à Trois-Rivières | 2025-02-01 |
| Longitudinal Study on Bacterial Production of LPC and LPA in Patients With Inflammatory Bowel Disease NCT06548399 | Recruiting | Ontario | McMaster University | 2024-12-01 | |
| Effectiveness of Penthrox vs Placebo in Sinus Procedures, a Clinical Trial NCT06750302 | Recruiting | Phase 1, Phase 2 | British Columbia | St. Paul's Hospital, Canada | 2024-11-24 |
| Music Intervention in Chronic Pain Patients NCT06436378 | Recruiting | Not applicable | Quebec | Laval University | 2024-05-28 |
| Alberta Chiropractic SelfBack Study NCT06347991 | Recruiting | Not applicable | Alberta | University of Alberta | 2024-05-24 |
| Perioperative Vitamin C to Reduce Persistent Pain After Total Knee Arthroplasty NCT06123715 | Recruiting | Phase 2 | Ontario | University Health Network, Toronto | 2024-04-16 |
| Emotion and Memory in Chronic Neuropathic Pain NCT06518421 | Recruiting | Ontario | University Health Network, Toronto | 2024-02-12 | |
| Self-hypnosis Training for Chronic Pain Management NCT06279650 | Recruiting | Not applicable | Quebec | Ciusss de L'Est de l'Île de Montréal | 2024-02-01 |
| Novel Use of Probenecid to Alleviate Symptoms of Opioid Withdrawal NCT04939623 | Recruiting | Phase 2 | Alberta | University of Calgary | 2023-10-31 |
| The METRIC Study Protocol NCT05986370 | Recruiting | Not applicable | Quebec | Université du Québec à Trois-Rivières | 2023-10-25 |
| UltrasouNd-guided Percutaneous Intercostal Nerve Cryoneurolysis for Analgesia Following Traumatic Rib Fracture NCT05865327 | Recruiting | Not applicable | Ontario | Sunnybrook Health Sciences Centre | 2023-10-23 |
| Brain, Psychological and Epigenetic Determinants for Optimizing the Treatment of Chronic Low Back Pain NCT05963451 | Recruiting | Quebec | Université de Sherbrooke | 2023-09-07 | |
| Evaluating a Virtual Stepped Care Portal in Youth Awaiting Tertiary Chronic Pain Care: An Implementation-Effectiveness Hybrid Type III Study NCT05894772 | Recruiting | Not applicable | Nova Scotia, Ontario, Quebec, Saskatchewan | The Hospital for Sick Children | 2023-08-05 |
| A Longitudinal Study Looking at the Prevalence, Risk Factors & Consequences of Persistent Post-surgical Pain in Children NCT06354699 | Recruiting | Telethon Kids Institute | 2023-06-26 | ||
| RTMS and Steroid Joint Steroid Injection in Chronic Spinal Pain NCT05840354 | Recruiting | Not applicable | Ontario | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2023-06-20 |
| Lemborexant vs Zopiclone vs Clonidine for Insomnia Treatment in Chronic Pain Patients NCT05618002 | Recruiting | British Columbia | Salem Anaesthesia Pain Clinic | 2022-11-08 | |
| Power Over Pain Portal: A Stepped-care Virtual Solution to Deliver Early Intervention to Canadian Youth With Chronic Pain NCT06076889 | Recruiting | Ontario | The Hospital for Sick Children | 2022-10-31 |
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.