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Chronic Low Back Pain: clinical trials and information

Chronic low back pain is back pain that lasts for 12 weeks or longer. In many cases no single specific cause is found. It is one of the most common reasons people see a health professional.
7
Trials with Canadian sites
0
Recruiting in Canada
384
Registry records worldwide

Chronic Low Back Pain clinical trials in Canada

7 trials, recruiting first
PhaseProvinces
Effects of a Myofascial Technique on Biomechanical Properties of the Lumbar Myofascia of Chronic Low Back Pain Adults
NCT04830566
CompletedNot applicableQuebecUniversité de Sherbrooke2021-03-19
The Effects Of Equal Breathing On Pain Pressure Thresholds
NCT03353142
Unknown statusNot applicableOntarioHamilton Health Sciences Corporation2018-02-01
Which Exercise for Low Back Pain: A Validation Study
NCT03327753
CompletedNot applicableOntarioMcMaster University2017-01-10
Investigation of a Physiotherapist and Nurse Practitioner Intervention for Chronic Low Back Disorders Delivered Through Telehealth
NCT02225535
CompletedNot applicableSaskatchewanUniversity of Saskatchewan2014-07
Use of Biofeedback Training to Correct Abnormal Neuromechanical Pattern in Chronic Low Back Pain Patients
NCT02239289
CompletedNot applicableQuebecUniversité du Québec à Trois-Rivières2014-03
Prognostic Factors of Disabling Low Back Pain in Patients With Chronic Low Back Pain
NCT02226692
CompletedQuebecUniversité du Québec à Trois-Rivières2011-10
Epidural Study of Patients With Chronic Lower Back Pain
NCT00887003
CompletedNot applicableOntarioMcMaster University2005-05

Chronic Low Back Pain clinical trials worldwide (outside Canada)

377 trials, 52 recruiting or not yet recruiting. Recruiting first.

PhaseCountries
Sensory Stimulation Belt for Chronic Low Back Pain in Office Workers
NCT07801755
Not yet recruitingNot applicableThailandMahidol University2028-01-01
Optimization of Lumbar Sensory Stimulation Parameters in Office Workers With Chronic Low Back Pain
NCT07801729
Not yet recruitingNot applicableThailandMahidol University2027-01-01
Investigating Novel Interventions for Low Back Pain in US Military Veterans: A Randomized Controlled Adaptive Phase II Trial
NCT05935761
Not yet recruitingPhase 2United StatesVA Office of Research and Development2026-12-01
Durability of Yoga for Veterans With Low Back Pain
NCT07053787
Not yet recruitingNot applicableUnited StatesVA Office of Research and Development2026-11-01
SERENITY Study of Chronic Pain Interference in Adults
NCT07820475
Not yet recruitingUnited StatesUniversity of Minnesota2026-11-01
Veterans' Intervention Blending NeuRomodulation and YogA for Chronic Low BackPaiN Treatment: VIBRANT
NCT07158567
Not yet recruitingPhase 3United StatesVA Office of Research and Development2026-10-14
Validating Blinding Maintenance of a Sham-Sensitization Control Design for Sensitization Acupuncture Trials
NCT07868224
Not yet recruitingNot applicableChinaJiangxi University of Traditional Chinese Medicine2026-10-10
Pain Neuroscience Education and Neuromuscular Exercise in Individuals With Chronic Low Back Pain and Central Sensitization
NCT07866690
Not yet recruitingNot applicableTurkey (Türkiye)Izmir Katip Celebi University2026-10
Evaluation of an Online Peri-operative Health Education Platform for Patients Undergoing Spine Surgery: Ready Set Recover
NCT07766824
Not yet recruitingEarly phase 1United StatesNational University of Natural Medicine2026-09-30
Assessment of Pain Perception and the Impact of Central Sensitization on Biopsychosocial Manifestations During Physical Activity in Patients With Chronic Low Back Pain
NCT07818551
Not yet recruitingNot applicableFranceUniversity Hospital, Brest2026-09-20
SPINE-RISK VE: Multimodal Predictive Model for Failed Back Surgery Syndrome in Venezuelan Surgical Patients
NCT07693517
Not yet recruitingVenezuelajuan jose valero quintero,MD2026-09-04
Efficacy of Low-Dose Laser Acupuncture for Low Back Pain
NCT07461363
Not yet recruitingNot applicableChinaMun Fei Yam2026-09-01
Association of Subcutaneous Fat Index, Paraspinal Muscle Characteristics, and Facet Morphology With Lumbar Facet Joint Degeneration
NCT07860697
RecruitingTurkey (Türkiye)Marmara University2026-09-01
Personalized and Automated Digital Coaching in People With Non-specific Chronic Low Back Pain
NCT06498271
Not yet recruitingNot applicableFranceAssistance Publique - Hôpitaux de Paris2026-09
Effect of Alexithymia on Treatment Response to Transforaminal Epidural Steroid Injections in Chronic Low Back Pain
NCT07828132
Not yet recruitingMarmara University2026-09
Study of Correlation Between the Level of Intradiscal Periostin Expression and Pfirrmann Grading
NCT07776366
RecruitingSouth KoreaKeimyung University Dongsan Medical Center2026-08-13
The Prediction of Clinical Outcome Using the Serum BDNF Level
NCT07776379
RecruitingSouth KoreaKeimyung University Dongsan Medical Center2026-08-13
Prospective Case Series Evaluating 6-Month and 12-Month Outcomes After Cryoneurolysis for Chronic Pain
NCT07639060
RecruitingUnited StatesYale University2026-06-20
Impact of Leisure Activities on Quality of Life in Low Back Pain
NCT07467499
RecruitingBelgiumCentre Hospitalier Valida2026-06-01
Ultrasound-Guided Proximal Superior Cluneal Nerve Block for Superior Cluneal Nerve Entrapment
NCT07712406
RecruitingTurkey (Türkiye)Gaziosmanpasa Research and Education Hospital2026-05-15
Treatment of Chronic Lower Back Pain With a Combination of Electrical Stimulation, LED, and Laser Therapy
NCT07313826
Not yet recruitingNot applicableUnited StatesDefense and Veterans Center for Integrative Pain Management2026-05-01
Efficacy of Cognitive Functional Therapy in Individuals With Chronic Low Back Pain After Spinal Surgery
NCT07576062
Not yet recruitingNot applicableCentro Universitário Augusto Motta2026-05
Virtual Reality-Based Rehabilitation Versus Conventional Therapy in Patients With Chronic Low Back Pain
NCT07463105
RecruitingNot applicablePolandUniversity of Rzeszow2026-04-01
Evaluation of Stabilization Training With Biofeedback in Lumbosacral Spine Pain Syndrome
NCT07463729
RecruitingNot applicablePolandUniversity of Rzeszow2026-04-01
Validation of a Virtual Reality Timed Up and Go Test in Adults With Chronic Non-Specific Low Back Pain
NCT07402499
Not yet recruitingTurkey (Türkiye)Selcuk University2026-03-21
Auricular Vagus Nerve Stimulation in Patients With High Impact Chronic Low Back Pain
NCT07681336
RecruitingNot applicableBelgiumAlgemeen Ziekenhuis Maria Middelares2026-03-04
Effect of Passive Versus Active Aquatic Therapy Compared With Conventional Physiotherapy for Chronic Low Back Pain
NCT07196826
Not yet recruitingNot applicableUnited Arab EmiratesGulf Medical University2026-02-20
MBM and taVNS for Low Back Pain and Depressive Symptoms
NCT07415941
RecruitingNot applicableUnited StatesFlorida State University2026-01-30
Pain Neuroscience Education Combined With Lumbar Stabilization Exercises on Disability and Kinesiophobia Among Patients With Chronic Low Back Pain
NCT07307859
Not yet recruitingNot applicableAl-Azhar University2026-01-20
Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression
NCT06419439
RecruitingPhase 2United StatesVA Office of Research and Development2025-12-03
Effectiveness of Thoracolumbar Fascia Mobilization and Ultrasound-Guided 5% Dextrose Injection in Chronic Low Back Pain
NCT07241559
RecruitingNot applicableTurkey (Türkiye)Ankara City Hospital Bilkent2025-11-01
The Effect of ESWT Added to Conservative Treatment on Pain, Disability, and Ultrasonographic Outcomes in Chronic Low Back Pain
NCT07132762
RecruitingNot applicableTurkey (Türkiye)Pamukkale University2025-10-10
Meditation for Older Adults With Chronic Low Back Pain
NCT06384001
RecruitingNot applicableUnited StatesFlorida State University2025-09-24
Physical Activity and Exercise for Disability and Improving Mental Health in Elderly With Chronic Low Back Pain
NCT07178561
RecruitingNot applicablePalestinian TerritoriesAl-Azhar University2025-09-10
Active Music-Based Intervention in Patients With Chronic Low Back Pain
NCT06940063
RecruitingNot applicableUnited StatesSharon Wang-Price2025-08-07
Expressive Art Therapy for Elder Adults With Chronic Low Back Pain
NCT07141082
RecruitingNot applicableHong KongThe Hong Kong Polytechnic University2025-08-02
High-Intensity Laser Therapy Versus Transforaminal Epidural Steroid Injection in Chronic Lumbar Disc Herniation-Related Low Back and Radicular Pain
NCT07688915
RecruitingNot applicableTurkey (Türkiye)Ankara City Hospital Bilkent2025-08-01
Effect of Kinetic Control in Lumbosacral Radiculopathy.
NCT07079202
Not yet recruitingNot applicableMadonna Maher Ezzat Yassa2025-07-17
The 6 Minute Step Test in Chronic Low Back Pain
NCT07028034
RecruitingTurkey (Türkiye)Kirsehir Ahi Evran Universitesi2025-06-25
Telerehabilitation for Patients With Chronic Low Back Pain (TeleBACK Clinical Trial)
NCT06821607
RecruitingNot applicableUnited StatesJohns Hopkins University2025-04-01
VRFR- Immersive Virtual Reality Use in a Spine Functional Restoration Program - A Feasibility Study
NCT06724679
RecruitingNot applicableFranceUniversity Hospital, Angers2025-03-19
The Relationship Between Upper Extremity Exercise Capacity, Respiratory and Peripheral Muscle Strength in Chronic Low Back Pain
NCT06806514
RecruitingTurkey (Türkiye)Kirsehir Ahi Evran Universitesi2025-02-03
Foot Reflexology for Chronic Low Back Pain
NCT06828016
RecruitingNot applicableTaiwanFu Jen Catholic University Hospital2025-01-18
Home-Based Rehabilitation Training for Chronic Low Back Pain Patients
NCT05998434
Not yet recruitingNot applicableFirst Affiliated Hospital, Sun Yat-Sen University2025-01-01
Contribution of the Podiatrist-Posturologist in the Evaluation of the Link Between the Stabilometric Parameters and the Pain Felt in Patients With Chronic Low Back Pain
NCT05540548
RecruitingFranceUniversity Hospital, Lille2024-06-11
Phenotyping Response to Spinal Cord Stimulation in Chronic Low Back Pain
NCT06310226
RecruitingNot applicableUnited StatesUniversity of California, Los Angeles2024-04-11
Mobile Neurofeedback for Low Back Pain
NCT05669027
RecruitingNot applicableUnited StatesDuke University2023-10-02
Transcranial Stimulation for Physiotherapy Optimisation - Chronic Low Back Pain (STOP-CLBP)
NCT05757609
RecruitingNot applicableSwitzerlandStephane ARMAND2023-08-21
Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response
NCT04142177
RecruitingNot applicableUnited StatesVA Office of Research and Development2022-06-13
Study of the Contribution of Osteopathic Treatment to Classic Medical Management in Patients With Chronic Low Back Pain
NCT03836248
RecruitingNot applicableFranceClinique Pasteur2019-10-02

About Chronic Low Back Pain

What is Chronic Low Back Pain?

Chronic low back pain is back pain that lasts for 12 weeks or longer. In many cases no single specific cause is found. It is one of the most common reasons people see a health professional.

How is Chronic Low Back Pain usually assessed?

Assessment usually involves a history and physical examination, with attention to warning signs that may need urgent investigation. Imaging is not needed in every case; clinicians decide based on symptoms and findings.

What kinds of treatments are studied for Chronic Low Back Pain?

Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.

How can I find Chronic Low Back Pain clinical trials in Canada?

This page lists 7 registry records for this term with at least one site in Canada, recruiting studies first. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.

Related conditions

Related interventions

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.