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Chronic Pain: clinical trials and information

"Chronic Pain" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 1972 chronic pain registry records worldwide.
134
Trials with Canadian sites
23
Recruiting in Canada
1972
Registry records worldwide

Chronic Pain clinical trials in Canada

134 trials, recruiting first
PhaseProvinces
Virtual Reality for Pain and Well-Being in Older Adults
NCT07607899
RecruitingNot applicableQuebecLaval University2026-09-14
Co-Adaptation of an Digital Pain Management Program for Canadian Veterans
NCT07818980
RecruitingOntarioUniversity Health Network, Toronto2026-09-14
Ketamine Assisted Psychotherapy for Treating Comorbid Chronic Pain and PTSD
NCT07009158
RecruitingPhase 1, Phase 2OntarioDr. Yuliya Knyahnytska2026-03-31
Accelerated Neuromodulation for Concurrent Post-Traumatic Stress Disorder (PTSD) & Chronic Pain in Veterans
NCT07192536
Not yet recruitingPhase 4British ColumbiaLegion Veterans Village Research Foundation2026-01
Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication
NCT05585229
RecruitingPhase 2British ColumbiaUniversity of British Columbia2025-10-27
Evaluation of a Mind-Body Based Approach for Chronic Pain Treatment
NCT07143396
Not yet recruitingNot applicableBritish ColumbiaUniversity of the Fraser Valley2025-10
Analgesia Nociception Index In Pediatric Patients With Chronic Pain
NCT07145762
Not yet recruitingQuebecMcGill University Health Centre/Research Institute of the McGill University Health Centre2025-09-15
Virtual Reality and Cranial Nerve Non-invasive Neuromodulation to Improve Quality of Life for Veterans
NCT07137845
Not yet recruitingNot applicableQuebecUniversité de Sherbrooke2025-09
Virtual Reality and Cranial Nerve Neuromodulation to Manage Chronic Pain
NCT07065396
Not yet recruitingNot applicableQuebecUniversité de Sherbrooke2025-07
Music as an Adjunct to Ketamine Therapy for Chronic Pain
NCT06994559
RecruitingNot applicableQuebecMcGill University2025-06-01
Comparison of the Efficacy of an Empowered Relief Single-Session Versus Standard Care for Reducing Postoperative Pain Following Elective Orthopedic Surgery: A Randomized Controlled Trial
NCT07392099
RecruitingNot applicableQuebecUniversité de Sherbrooke2025-05-05
Treatment With Psilocybin for Chronic Neuropathic Pain and Depression (TRANSCEND)
NCT06518720
RecruitingPhase 2OntarioCentre for Addiction and Mental Health2025-04-01
Music Intervention in Chronic Pain Patients
NCT06436378
RecruitingNot applicableQuebecLaval University2024-05-28
Perioperative Vitamin C to Reduce Persistent Pain After Total Knee Arthroplasty
NCT06123715
RecruitingPhase 2OntarioUniversity Health Network, Toronto2024-04-16
Novel Use of Probenecid to Alleviate Symptoms of Opioid Withdrawal
NCT04939623
RecruitingPhase 2AlbertaUniversity of Calgary2023-10-31
Evaluating a Virtual Stepped Care Portal in Youth Awaiting Tertiary Chronic Pain Care: An Implementation-Effectiveness Hybrid Type III Study
NCT05894772
RecruitingNot applicableNova Scotia, Ontario, Quebec, SaskatchewanThe Hospital for Sick Children2023-08-05
A Longitudinal Study Looking at the Prevalence, Risk Factors & Consequences of Persistent Post-surgical Pain in Children
NCT06354699
RecruitingTelethon Kids Institute2023-06-26
Lemborexant vs Zopiclone vs Clonidine for Insomnia Treatment in Chronic Pain Patients
NCT05618002
RecruitingBritish ColumbiaSalem Anaesthesia Pain Clinic2022-11-08
Power Over Pain Portal: A Stepped-care Virtual Solution to Deliver Early Intervention to Canadian Youth With Chronic Pain
NCT06076889
RecruitingOntarioThe Hospital for Sick Children2022-10-31
Mechanisms and Outcome-Prognostication for Paresthesia-based and -Free Spinal Cord Stimulation
NCT03852381
RecruitingNot applicableOntarioUniversity Health Network, Toronto2019-05-16
Reducing Opioid Use for Chronic Pain Patients Following Surgery
NCT03675386
RecruitingNot applicableOntarioUniversity Health Network, Toronto2018-10-15
Pain Clinic Provides Public Health Safety
NCT06076512
RecruitingBritish ColumbiaSalem Anaesthesia Pain Clinic2018-02-02
Characteristics of Injury Claims by Chronic Pain Patients
NCT06104384
RecruitingBritish ColumbiaSalem Anaesthesia Pain Clinic2018-01-02
Patient Education, Self-management and Physiotherapy for Chronic Temporomandibular Disorders
NCT07423234
Active, not recruitingNot applicableQuebecCiusss de L'Est de l'Île de Montréal2026-01-16
Complex Regional Pain Syndrome: Analgesic Outcome
NCT07228949
CompletedQuebecCiusss de L'Est de l'Île de Montréal2025-11-15
Pharmacogenetic Testing and Chronic Pain
NCT05259865
SuspendedOntarioCanadian Forces Health Services Centre Ottawa2025-09-21
3-point vs 6-point GNRFA for Chronic KOA
NCT05930756
WithdrawnNot applicableOntarioMcMaster University2025-08-09
Physiological Impact of Different Types of Osteoarthritis Education.
NCT06400329
CompletedNot applicableOntarioLisa Carlesso2024-08-15
Pain Education Program Optimization (PEPO) Trial
NCT06174246
Unknown statusNot applicableLaval University2023-12-11
Intercostal Cryoanalgesia for Chronic Pain After VATS Lung Resection
NCT05884099
CompletedNot applicableQuebecCentre hospitalier de l'Université de Montréal (CHUM)2023-11-09
Superficial Parasternal Intercostal Plane Block in Cardiac Surgery Trial
NCT06028126
CompletedNot applicableAlberta, British Columbia, Nova Scotia, OntarioUnity Health Toronto2023-09-08
Brain MRI for Knee OA
NCT05986513
Unknown statusNot applicableOntarioToronto Rehabilitation Institute2023-09-01
Using Peripheral Neurostimulation to Improve Work Rehabilitation
NCT05316623
Unknown statusNot applicableQuebecUniversité de Sherbrooke2023-08-08
The Young Adult Clinic (YAC) Study
NCT05147974
CompletedNot applicableOntarioWomen's College Hospital2023-04-20
A Randomized, Controlled Study of Repeat Dose Sustained Release Lidocaine for Treatment of Chronic Scrotal Pain
NCT05707208
CompletedPhase 2Alberta, British Columbia, Manitoba, Ontario, QuebecSustained Therapeutics Inc.2023-03-21
Aquatic Exercise for Veterans in Pain
NCT05869617
Unknown statusNot applicableOntarioDr. Nicholas Held2023-01-27
Aging, Mobility and Chronic Low Back Pain
NCT05167877
CompletedOntarioMcMaster University2023-01-15
Improving Pain Disability With the Use of Oral Cannabinoids
NCT05351905
CompletedNot applicableOntarioUniversity Health Network, Toronto2022-11-22
Evaluation of a Pilot Shard-care Program for Patients With Chronic Pain in the Champlain-LHIN
NCT03531476
Unknown statusNot applicableOntarioOttawa Hospital Research Institute2022-09
Development and Feasibility Testing of an Advanced Practice Physiotherapy Role in Chronic Pain Management
NCT05336903
CompletedNot applicableOntarioJordan Miller, PT, PhD2022-06-24
Feasibility Study of an Online Self-management Program for Chronic Non-cancer Pain
NCT05319652
CompletedNot applicableQuebecCHU de Quebec-Universite Laval2022-06-06
Palisade Lateral Branch Technique Using Multi-tined Needles for Sacro-iliac Joint Radiofrequency Ablation
NCT05043961
TerminatedQuebecCiusss de L'Est de l'Île de Montréal2022-06-01
WebMAP for Childhood Cancer Survivors
NCT05241717
Unknown statusNot applicableAlbertaUniversity of Calgary2022-06
Transcranial Direct Current Stimulation in Clinical Setting to Reduce Pain in Older Workers
NCT05370833
Unknown statusNot applicableQuebecUniversité de Sherbrooke2022-05-15
DNIC Using Deep Learning and Artificial Intelligence
NCT04896827
SuspendedQuebecUniversité de Sherbrooke2022-04-05
Evaluating the Efficacy of Intranasal Oxytocin on Chronic Pain
NCT04903002
Active, not recruitingPhase 2, Phase 3Alberta, British Columbia, Newfoundland and LabradorMemorial University of Newfoundland2022-04-01
Persistent Opioid Consumption After Major Abdominal Surgery and Its Determinants
NCT05197465
CompletedQuebecCentre hospitalier de l'Université de Montréal (CHUM)2022-02-13
Neuromodulation Parameter Efficacy
NCT04933370
Unknown statusNot applicableAlbertaAlberta Health Services, Calgary2022-02-01
French Version of Fear-Avoidance Component Scale (FACS-FR)
NCT05217017
CompletedNot applicableQuebecUniversité de Sherbrooke2022-02-01
Evaluation of a Mind-body Based Application for the Treatment of Chronic/Persistent Pain.
NCT05090683
CompletedNot applicableBritish ColumbiaUniversity of the Fraser Valley2021-10-15

Chronic Pain clinical trials worldwide (outside Canada)

1838 trials, 308 recruiting or not yet recruiting. Recruiting first.

PhaseCountries
Personalizing Veteran Pain Care: Adapting Coaching Interventions to Support Maintenance of Self-Care
NCT07456150
Not yet recruitingPhase 1United StatesVA Office of Research and Development2029-01-01
DockTales for Chronic Pain
NCT07680894
Not yet recruitingNot applicableUnited StatesUniversity of Maryland, Baltimore2027-07-17
Mindfulness Therapy for Chronic Pain After Intimate Partner Violence
NCT07700355
Not yet recruitingNot applicableUnited StatesBrigham and Women's Hospital2027-07
Multicomponent Pain Self-Management in Adults With Haemophilic Arthropathy
NCT07860632
Not yet recruitingNot applicableSpainInvestigación en Hemofilia y Fisioterapia2027-03-01
Nurse-Delivered Brief Pain Relief Skills Treatment in Rural Communities
NCT07863375
Not yet recruitingNot applicableUnited StatesWashington State University2027-03-01
Healing Gardens: Leveraging Serious Games to Deliver Accessible Pain-CBT and Pharmacologic Support for Patients With Advanced Cancer Managing Pain
NCT07825051
Not yet recruitingNot applicableUnited StatesDana-Farber Cancer Institute2027-02-13
Integrated Digital Health Approach to Reduce Hazardous Alcohol Use and Chronic Pain Among Rural Populations
NCT07804914
Not yet recruitingNot applicableUnited StatesBoston University Charles River Campus2027-02-01
MBI for Pain and Sleep in Adolescents and Young Adults With Sickle Cell Disease
NCT07797582
Not yet recruitingNot applicableUniversity of Illinois at Chicago2027-02
"Evaluation of the Efficacy of Intravenous Lidocaine on Chronic Post-operative Pain in Patients Requiring Emergency Abdominal Surgery. A Multicentre, Randomised, Controlled, Double-blind Study."
NCT07869173
Not yet recruitingPhase 3FranceNantes University Hospital2027-01-15
Neurobiology of Pain in Burn Survivors
NCT07824635
Not yet recruitingNot applicableSpaulding Rehabilitation Hospital2027-01
Turkish Version of a Scale Measuring How People View Chronic Pain
NCT07861698
Not yet recruitingTurkey (Türkiye)Bilecik Seyh Edebali Universitesi2026-12-15
Ketamine-Assisted Psychotherapy for Treatment-Resistant Depression
NCT07247006
Not yet recruitingPhase 2United StatesUniversity of Rochester2026-12
Digital Treatment for Chronic Pain and Addiction in Veterans With Opioid Use Disorder Receiving Buprenorphine
NCT07361432
Not yet recruitingPhase 3United StatesVA Office of Research and Development2026-11-02
SERENITY Study of Chronic Pain Interference in Adults
NCT07820475
Not yet recruitingUnited StatesUniversity of Minnesota2026-11-01
The Serial Mediating Roles of Pain Acceptance and Pain Self-Efficacy in the Relationship Between Concerns About Pain and Well-Being in Pain Among Individuals With Chronic Pain: A Structural Equation Modeling Study
NCT07846514
Not yet recruitingTurkey (Türkiye)Bilecik Seyh Edebali Universitesi2026-11-01
Effectiveness of Resonance Frequency Breathing Exercises in Patients With Systemic Lupus Erythematosus and Central Sensitization
NCT07868289
Not yet recruitingNot applicableTurkey (Türkiye)Istanbul University - Cerrahpasa2026-11-01
Transcranial Electrical Stimulation for Comorbid Depression and Chronic Pain
NCT07334561
RecruitingNot applicableChinaShanghai Mental Health Center2026-11
Pain Resilience and Pain Self-Efficacy as Parallel Mediators of the Relationship Between Self-Critical Rumination and Pain-Specific Well-Being in Individuals With Chronic Pain: A Structural Equation Modeling Study
NCT07846540
Not yet recruitingTurkey (Türkiye)Bilecik Seyh Edebali Universitesi2026-10-31
Mindfulness-Based Cognitive Therapy Vs. the Health Enhancement Program for Chronic Pain and Early Cognitive Decline; The Feeling of Being Pilot RCT
NCT07785648
Not yet recruitingNot applicableUnited StatesMassachusetts General Hospital2026-10-18
Reducing Chronic Pain Following Cesarean Delivery
NCT07799883
RecruitingNot applicableUnited StatesStanford University2026-10-05
Empowered Relief for Severe Pain After Cesarean Delivery During the Inpatient Period
NCT07832240
Not yet recruitingNot applicableUnited StatesStanford University2026-10-05
Tai Chi Intervention for Geriatric Pain Syndrome
NCT03705598
RecruitingNot applicableUnited StatesUniversity of Massachusetts, Boston2026-10-01
The Women Veteran's Health Mission
NCT07608952
Not yet recruitingNot applicableMcGill University Health Centre/Research Institute of the McGill University Health Centre2026-10-01
Development of a Pain Rehabilitation Program for Chronic Pain After SCI
NCT07634796
Not yet recruitingNot applicableSwedenUmeå University2026-10-01
Perioperative Yoga Therapy and Endometriosis Surgery
NCT07765680
Not yet recruitingNot applicableFranceUniversity Hospital, Lille2026-10-01
Comparing Patient-Reported Symptoms to Objective Neck Range of Motion and Physical Capacity in Women With Chronic Neck Pain.
NCT07862387
Not yet recruitingBorna Farhoomand2026-10-01
Pediatric Electrocutaneous Analgesia for Children Experiencing Neuropathic Pain
NCT07264920
Not yet recruitingNot applicableUnited StatesJohns Hopkins University2026-10
Biopsychosocial Risk Influences on the Development and Generation of Early-Onset Chronic Pain
NCT07602595
RecruitingUnited StatesChildren's Hospital Medical Center, Cincinnati2026-10
Empowered Relief for Caregivers
NCT07636980
Not yet recruitingNot applicableUnited StatesStanford University2026-10
Outcomes Registry After Ketamine Infusions for Chronic Pain: A Longitudinal Evaluation
NCT07648771
Not yet recruitingUnited StatesStanford University2026-10
LIFU for Chronic Pain and Generalized Anxiety Disorder
NCT07686354
Not yet recruitingNot applicableUnited StatesVirginia Polytechnic Institute and State University2026-10
Feasibility and Acceptability of Empowered Relief for American Indians With Pain During and After Cancer Treatment
NCT07742449
Not yet recruitingNot applicableUnited StatesUniversity of Oklahoma2026-10
Virtual Reality-Based Hypnotherapy for Pain, Sleep, and Mood in Spinal Cord Injury
NCT07846410
Not yet recruitingNot applicableTurkey (Türkiye)Istanbul Physical Medicine Rehabilitation Training and Research Hospital2026-10
Concurrent tDCS for Chronic Pain in Adults With Cerebral Palsy
NCT07846436
Not yet recruitingNot applicableGillette Children's Specialty Healthcare2026-10
Evaluation of Chronic Postsurgical Pain Risk in Patients Undergoing CIED Implantation Using an AID Support System
NCT07322900
Not yet recruitingIstanbul University - Cerrahpasa2026-09-30
BurstDR Spinal Cord Stimulation Versus Sham in Established Responders
NCT07779733
Not yet recruitingNot applicableSwedenUmeå University2026-09-30
Virtual Pain Education for Spinal Cord Stimulation Patients
NCT07743905
Not yet recruitingNot applicableUniversity of Arkansas2026-09-09
Validation of the Turkish Brief Inventory of Treatment Expectations in Chronic Pain
NCT07673874
Not yet recruitingTurkey (Türkiye)Hacettepe University2026-09-01
Turkish Adaptation of the Pain and Smoking Inventory
NCT07673926
Not yet recruitingTurkey (Türkiye)Hacettepe University2026-09-01
Full-Spectrum Cannabis Extract for Chronic Pain and Bone Health Biomarkers in Women
NCT07783295
Not yet recruitingPhase 2BrazilAssociação Pan-Americana Multidisciplinar de Endocanabinologia2026-09-01
Internet-Delivered Acceptance and Commitment Therapy (iACT) for Youth With PTSD and Chronic Pain
NCT07813728
RecruitingNot applicableSwedenSkane University Hospital2026-09-01
Harmonized Healing: Personalized Music Interventions to Address Chronic Pain in People Living With HIV
NCT07214077
Not yet recruitingNot applicableBrigham and Women's Hospital2026-09
Personalized Care Management Model (GAP-421) for Chronic Pain in Primary Care Physiotherapy
NCT07451587
Not yet recruitingNot applicableSpainUniversidad Autonoma de Madrid2026-09
Analgesic Efficacy of Multisite rTMS in Fibromyalgia Patients
NCT07642882
RecruitingNot applicableFranceHospital Ambroise Paré Paris2026-09
Human Pain Atlas for Sensory Neurons
NCT07740681
Not yet recruitingKing's College Hospital NHS Trust2026-09
S1R Imaging-Based Cryoneurolysis in Chronic Pain
NCT07768501
Not yet recruitingEarly phase 1Davidzon, Guido, M.D.2026-09
Alexithymia, Pain Intensity, Quality of Life, and Psychological Symptoms in Chronic Coccydynia Patients Scheduled for Ganglion Impar Block
NCT07828145
Not yet recruitingTurkey (Türkiye)Marmara University2026-09
A Study of Cebranopadol for Opioid Withdrawal Symptoms in Adults With Chronic Pain
NCT07874620
Not yet recruitingPhase 2United StatesAdneuris Therapeutics, Inc.2026-09
Action Observation and Motor Imagery Training in Cervical Disc Herniation
NCT07781982
Not yet recruitingNot applicableİrem Çetinkaya2026-08-25
Effect of Rebound Pain on Chronic Postsurgical Pain After Total Knee Arthroplasty
NCT07511985
RecruitingTurkey (Türkiye)Konya City Hospital2026-08-19

About Chronic Pain

What is Chronic Pain?

"Chronic Pain" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 1972 chronic pain registry records worldwide.

How is Chronic Pain usually assessed?

Assessment of chronic pain generally involves a clinician taking a detailed history, a physical examination and, where relevant, tests to look for underlying causes. Pain rating scales and questionnaires about function, sleep and mood are often used. The approach depends on the person and the condition.

What kinds of treatments are studied for Chronic Pain?

Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.

How can I find Chronic Pain clinical trials in Canada?

This page lists 134 registry records for this term with at least one site in Canada, recruiting studies first. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.

Related interventions

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.