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Pain, Chronic: clinical trials and information

"Pain, Chronic" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 353 chronic pain registry records worldwide.
16
Trials with Canadian sites
2
Recruiting in Canada
353
Registry records worldwide

Pain, Chronic clinical trials in Canada

16 trials, recruiting first
PhaseProvinces
UltrasouNd-guided Percutaneous Intercostal Nerve Cryoneurolysis for Analgesia Following Traumatic Rib Fracture
NCT05865327
RecruitingNot applicableOntarioSunnybrook Health Sciences Centre2023-10-23
iCanCope With Post-Operative Pain (iCanCope PostOp)
NCT05382962
RecruitingNot applicableOntarioThe Hospital for Sick Children2021-09-28
Online Psychology Program for Chronic Pain After Surgery
NCT06455345
CompletedNot applicableOntarioUniversity Health Network, Toronto2024-01-20
Relieving Chronic Pain in Older Adults With Transcranial Direct Current Stimulation
NCT05617027
Unknown statusNot applicableQuebecUniversité de Sherbrooke2023-10-19
PR-VR At-home Program During and After COVID-19
NCT04912817
CompletedNot applicableOntarioThe Hospital for Sick Children2022-09-01
Clonidine is Better Than Zopiclone for Insomnia Treatment in Chronic Pain Patients
NCT05277038
CompletedBritish ColumbiaSalem Anaesthesia Pain Clinic2022-03-01
Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN)
NCT04874038
Active, not recruitingPhase 3Alberta, Newfoundland and Labrador, Nova Scotia, Ontario, QuebecUniversity Health Network, Toronto2021-09-22
Development and Usability Testing of a Progressive WebApp for Women With Heart Disease
NCT03800082
Unknown statusNot applicableOntarioUniversity of Toronto2021-08-01
Evaluation of a Patient-Centred, Multidisciplinary Opioid Tapering Program for Individuals With Chronic Non-Cancer Pain on Long Term Opioid Therapy
NCT04902547
CompletedNot applicableManitobaUniversity of Manitoba2021-05-01
Cognitive Behavioural Therapy to Optimize Post-Operative Recovery Trial
NCT04274530
CompletedNot applicableAlberta, Newfoundland and Labrador, OntarioMcMaster University2021-01-25
SPRINT: Signature for Pain Recovery IN Teens
NCT04285112
Active, not recruitingOntarioStanford University2020-09-28
myoActivation® for Chronic Pain in a Marginalized Population
NCT04261959
CompletedBritish ColumbiaUniversity of British Columbia2020-02-18
Intercostobrachial Nerve Sparing to Reduce Post-Surgical Pain
NCT03421522
Unknown statusNot applicableOntarioMcMaster University2019-10-15
Pawsitive Impacts of Therapy Dog Visits
NCT04727749
CompletedNot applicableSaskatchewanUniversity of Saskatchewan2019-06-07
Trial Applying Policy to Eliminate or Reduce Inappropriate Narcotics in the General-population
NCT03400384
CompletedNot applicableQuebecCentre de Recherche de l'Institut Universitaire de Geriatrie de Montreal2018-07-17
Lidocaine Infusions for Chronic Pain in Children
NCT02983682
CompletedPhase 3OntarioThe Hospital for Sick Children2017-01

Pain, Chronic clinical trials worldwide (outside Canada)

337 trials, 45 recruiting or not yet recruiting. Recruiting first.

PhaseCountries
Mantram Repetition Versus Health Education for Veterans With PTSD and Chronic Pain
NCT07725588
Not yet recruitingNot applicableUnited StatesVA Office of Research and Development2027-04-01
RUTISS-Diary and RUTISS-65 Study
NCT07698041
Not yet recruitingUnited KingdomKatherine Finlay2026-07-08
Person-Centred AI Support in Interdisciplinary Rehabilitation for Chronic Pain
NCT07081737
Not yet recruitingNot applicableSwedenBjorn Ang2026-05-01
Ultrasound Guided Pecs Block and Ketamine Infusion for Preventing Chronic Pain in Patients Undergoing Breast Cancer Surgery
NCT07197684
Not yet recruitingNot applicableAga Khan University2026-03-16
Interoceptive Awareness and Function in Adolescents With Chronic Pain
NCT07325110
RecruitingUnited StatesConnecticut Children's Medical Center2026-02-25
Home-based Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for IBS Pain
NCT06847360
RecruitingNot applicableUnited StatesYale University2026-01-19
Butyrate and Taurine for Chronic Postsurgical Pain in Adult Cardiac Surgical Patients
NCT07144033
Not yet recruitingNot applicableHong KongChinese University of Hong Kong2026-01-01
Pain Reprocessing Therapy in Post-Operative Knee Pain
NCT06800209
RecruitingPhase 2United StatesWeill Medical College of Cornell University2025-08-13
Developing a Nonpharmacological Pain Intervention for Community-dwelling Older Adults With Dementia
NCT06264362
Not yet recruitingNot applicableUnited StatesDrexel University2025-06-02
The PROACTIVE Study for Black Elders
NCT06512727
RecruitingNot applicableUnited StatesUniversity of Florida2025-05-07
Methadone Dose Monitoring With a Remote Medication Monitor
NCT06837571
Not yet recruitingUnited StatesCari Health Inc.2025-04-26
Prescription Opioids, Brain Structure, and Cognition in Older Adults With Chronic Pain
NCT06837857
RecruitingPhase 2United StatesMayo Clinic2025-04-16
Prospective Validation Study of an E-health Tool for Patient Selection for SCS
NCT06853795
Not yet recruitingErasmus Medical Center2025-03-01
Sleep Well Despite Persistent Pain Symptoms
NCT06351839
RecruitingNot applicableNorwayUniversity of Tromso2025-01-01
Investigation of Grip Strength, Pain and Anxiety Levels in Dentists
NCT06721117
Not yet recruitingHacettepe University2024-12-01
Adolescent Outcomes of Post-operative Opioid EXposure
NCT06350409
RecruitingUnited StatesSharon Levy2024-11-12
Ziconotide for Non-cancer Pain by Intrathecal Administration
NCT06541184
RecruitingFranceESTEVE Pharmaceuticals SAS2024-10-30
Feasibility of Using an App for Managing Phantom Limb Pain Associated with Combat Injury in Ukraine (PAMELA)
NCT06604507
Not yet recruitingUkraineWinfried Meißner2024-10-15
Affecting Factors for Chronic Pain After Sternotomy
NCT06534372
RecruitingTurkey (Türkiye)Ankara Etlik City Hospital2024-09-01
Assessment of Methadone Dose Taken
NCT05981573
RecruitingUnited StatesCari Health Inc.2024-08-26
Nutrition Care in Patients Living With Chronic Pain
NCT06277232
RecruitingNot applicableSwedenLinkoeping University2024-08-01
Embo Registry; National Registry for Artery Embolization
NCT06477965
RecruitingUnited StatesVascular Solutions of North Carolina2024-07-15
Stellate Ganglion Block for Prevention of Post Mastectomy Depression
NCT06263907
RecruitingNot applicableEgyptMansoura University2024-03-01
MIVetsCan: Cannabidiol (CBD)-Care Trial
NCT06213233
RecruitingPhase 2United StatesKevin Boehnke2024-02-12
Evaluation of Cognitive Behavioral Therapy for Long-term Pain in Rheumatic Disease, Including Validation of AE-FS
NCT06413914
RecruitingNot applicableNorwayDiakonhjemmet Hospital2024-01-16
VR and Cooled Genicular Nerve Radio Frequency Ablation for Chronic Knee Pain
NCT06336447
RecruitingNot applicableUnited StatesNorthwestern University2024-01-12
Evaluating the Efficacy of the Pain Identification and Communication Toolkit
NCT06168604
RecruitingNot applicableUnited StatesWeill Medical College of Cornell University2023-12-14
Translation and Validation of the COMM and ASI-SR
NCT06084520
RecruitingSwedenUppsala University2023-12-01
Pain AND Opioids After Surgery
NCT05877157
RecruitingCroatia, United KingdomUniversity of Aberdeen2023-09-25
Screening Trial for Pain Relief in Schwannomatosis (STARFISH)
NCT05684692
RecruitingPhase 2United StatesMassachusetts General Hospital2023-08-31
7 Tesla MRI Brain Imaging to Decipher Filgotinib's Mode of Analgesic Action in Rheumatoid Arthritis
NCT05697159
RecruitingUnited KingdomNHS Greater Glasgow and Clyde2023-08-22
Perfusion MRI-targeted Joint Embolization for Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee
NCT05700682
RecruitingUnited StatesPalo Alto Veterans Institute for Research2023-07-15
Offset Mechanisms in Evaluation of Lumbar Medial Branch Blocks
NCT05961800
RecruitingNot applicableUnited StatesUniversity of Pittsburgh2023-07-05
Sleep, Pain and Stress in Adolescents With Persistent Pain
NCT05677412
RecruitingNot applicableFinlandHelsinki University Central Hospital2023-05-23
Predictive and Impact of Pain After 6 Months of Radiotherapy, in Head and Neck Cancer
NCT05505188
RecruitingNot applicableFranceUniversity Hospital, Caen2023-03-13
Comparative Effectiveness of Online 8-session CBT vs. 1-Session Empowered Relief for Chronic Pain - The PROGRESS Study
NCT05612750
RecruitingNot applicableUnited StatesStanford University2023-01-01
Opioid-free Anaesthesia in Breast Cancer Surgery
NCT06404983
RecruitingNot applicableGreeceUniversity of Ioannina2022-12-28
Prospective Study of Sensation and Satisfaction in Cancer and Transgender Mastectomy Patients
NCT06094257
RecruitingUnited StatesWeill Medical College of Cornell University2022-02-09
Diabetic Neuropathy in Spinal Cord Stimulator Patients
NCT04687215
RecruitingUnited StatesUniversity of Chicago2022-01-27
A Study to Reduce Persistent Post-mastectomy Pain Using Opioid-free Anesthesia
NCT05146778
RecruitingNot applicableSouth KoreaGangnam Severance Hospital2021-12-16
fMRI and IVCM Cornea Microscopy of CXL in Keratoconus
NCT04439552
RecruitingUnited StatesBoston Children's Hospital2021-10-04
Using Technology to Track Pain and Pain-related Outcomes
NCT04267588
RecruitingUnited StatesJohns Hopkins University2020-08-10
Pain and Weight Treatment: Development and Trial of PAW
NCT04046562
RecruitingNot applicableUnited StatesConnecticut Children's Medical Center2019-08-14
Evaluate the Impact of Targeted Physical Activity on Clinically Debilitated Dialysis Patients.
NCT06374537
RecruitingNot applicableUnited StatesUniversity of Illinois at Chicago2019-05-22
Evaluation of the PACE/PACENET BHL Clinical Program
NCT02463266
RecruitingUnited StatesUniversity of Pennsylvania2014-03
Efficacy and Safety of Canadá Association in the Treatment of Chronic Pain
NCT05125978
WithdrawnPhase 2EMS2026-09
Pain-at-Work Toolkit (Definitive Trial)
NCT07600892
Enrolling by invitationNot applicableUnited KingdomUniversity of Nottingham2026-05-11
Effectiveness of the Sana Device on Fibromyalgia Symptoms
NCT05394610
WithdrawnNot applicableSana Health2025-12
Cognitive Behavioral Therapy for Chronic Pain in Adults With Cerebral Palsy
NCT06269926
Active, not recruitingNot applicableUnited StatesHugo W. Moser Research Institute at Kennedy Krieger, Inc.2025-02-27
Physical Activity and Percussive Massage Therapy for Reducing Pain in Older Women
NCT07056335
CompletedNot applicableUnited StatesUniversity of Michigan2025-01-15

About Pain, Chronic

What is Pain, Chronic?

"Pain, Chronic" is the term study registrants used on ClinicalTrials.gov. Registry labels are not always standard medical terms, and close variants of the same label appear as separate entries. In this snapshot the term appears on 353 chronic pain registry records worldwide.

How is Pain, Chronic usually assessed?

Assessment of chronic pain generally involves a clinician taking a detailed history, a physical examination and, where relevant, tests to look for underlying causes. Pain rating scales and questionnaires about function, sleep and mood are often used. The approach depends on the person and the condition.

What kinds of treatments are studied for Pain, Chronic?

Registered studies cover medicines, medical devices (such as nerve stimulators), procedures (such as nerve blocks or injections), physical and movement therapies, psychological approaches (such as cognitive behavioural therapy), education programs and digital tools. Being studied in a trial does not mean a treatment works or is approved. The interventions listed on this page come directly from the registry records.

How can I find Pain, Chronic clinical trials in Canada?

This page lists 16 registry records for this term with at least one site in Canada, recruiting studies first. Each trial page links to the official ClinicalTrials.gov record, which lists the study contacts. Recruiting status changes often, so check the registry, and talk to your doctor before joining a study.

Related interventions

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status.