Comparison of ESWL Alone and ESWL + Endoscopy for Painful Chronic Pancreatitis
CompletedPhase 1, Phase 2NCT00133835
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Endoscopy is an established method of treatment for painful obstructive calcified pancreatitis. It involves the disintegration of calcifications using extracorporeal shock wave lithotripsy (ESWL) followed by endoscopic removal of stone fragments possibly associated with stent insertion. A pilot study suggests that ESWL alone relieves pain in calcified chronic pancreatitis (CP). The aim of this study is to compare both techniques in a randomized controlled trial.
Study details
- Official title
- Comparison of ESWL Alone and ESWL Combined With Endoscopic Drainage of the Main Pancreatic Duct for Painful Chronic Pancreatitis
- Conditions
- Pancreatitis
- Interventions
- Procedure: Extracorporeal shock wave lithotripsy
- Procedure: Endoscopic drainage of the main pancreatic duct
- Sponsor
- Erasme University Hospital
- Start date
- 1998-03
- Primary completion
- 2022-02-21
- Sex
- All
- Age range
- from 18 Years
- Results posted
- No results posted in this snapshot
- Countries
- Belgium, Italy
- Total sites listed
- 2
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Painful chronic pancreatitis (\>1 abdominal pain attack during the preceding 12 months) * At least 1 calcified stone greater than 4 mm in one of its axes in the cephalic or corporeal portion of the main pancreatic duct (MPD) with upstream duct dilation * Written informed consent obtained from the patient Exclusion Criteria: * History of treatment of the pancreas using ESWL, endoscopy, or surgery * Pancreatic collection greater than 2 cm in diameter at magnetic resonance or CT scan * Alkaline phosphatase levels greater than twice the upper limit of normal values or signs of cholangitis * Age below 18 years * Pregnancy or lactation
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT00133835