Intraoperative Nitrous Oxide and Postoperative Pain for Patients With Current Opioid Treatment
CompletedPhase 2NCT00210158
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Peroperative opioids are known to induce N-Methyl-D-Aspartate dependent enhancement of postoperative hyperalgesia. For patients with current opioid treatment, these phenomena could be exagerated and could produce greater postoperative opioid consumption and higher pain score. Since Nitrous oxide has anti- N-Methyl-D-Aspartate properties, the aim of this study was to evaluate, in patients with current opioid treatment, the effects of peroperative Nitous oxide on postoperative opioid consumption and pain score, after vertebroplasty.
Study details
- Official title
- Effects of Intraoperative Nitrous Oxide on Postoperative Pain for Patients With Current Opioid Treatment After Vertebroplasty.
- Conditions
- Interventions
- Procedure: Air
- Procedure: Protox
- Sponsor
- Institut Bergonié
- Start date
- 2005-01-01
- Primary completion
- 2006-12-31
- Sex
- All
- Age range
- from 18 Years to 100 Years
- Results posted
- Yes, on ClinicalTrials.gov
- Countries
- France
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
* Older than 18 years * Current opioid treatment \> 1 month * patients scheduled to undergo vertebroplasty with general anesthesia
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT00210158