Skip to content

Clinical Study on Implicit Learning, Comorbidity and Stress Vulnerability in Chronic Functional Pain

Unknown statusNot applicableNCT00222209
View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

The project investigates on the role of pain avoidance, comorbidity and stress response for the development of chronic somatic and visceral pain. We, the researchers at University Hospital Mannheim, assume that implicit operant learning of pain sensitization is a central mechanism of the process of pain becoming chronic, which is augmented by fear and by avoidance behaviour. Somatic and psychological comorbidity as well as stress factors are further promoting factors in chronic pain development.

Study details

Official title
Implicit Learning, Comorbidity and Stress Vulnerability in Chronic Functional Pain Syndromes
Interventions
  • Behavioral: Experimental heat pain model
Sponsor
Universitätsmedizin Mannheim
Collaborators
German Research Foundation
Start date
2005-09
Sex
All
Age range
from 20 Years to 70 Years
Healthy volunteers
true
Results posted
No results posted in this snapshot
Countries
Germany
Total sites listed
1

Eligibility criteria

Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Fibromyalgia according to American College of Rheumatology (ACR) criteria * Visceral hypersensitivity according to ROME criteria * Chronic pain according to International Association for the Study of Pain (IASP) criteria Exclusion Criteria: * Abnormal quantitative sensory testing * Psychiatric or neurological anamnesis, except fear and depression * Acute major depression * Substance abuse

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT00222209