Cytokine Regulation of Periradicular Pain in Humans
CompletedNCT00223470
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
This clinical trial evaluates the role of cytokines in patients needing root canal treatment with diagnosis of necrotic pulp and chronic apical periodontitis
Study details
- Official title
- Cytokine Regulation of Periradicular Pain in Humans
- Conditions
- Chronic Apical Periodontitis of Pulpal Origin
- Sponsor
- The University of Texas Health Science Center at San Antonio
- Collaborators
- National Institutes of Health (NIH); National Institute of Dental and Craniofacial Research (NIDCR)
- Start date
- 2002-10
- Primary completion
- 2008-06
- Sex
- All
- Age range
- from 16 Years to 60 Years
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: 1. Patient must be at least 16 years of age. 2. Clinical indication for Non-Surgical Root Canal Therapy (NSRCT). 3. 1st or 2nd maxillary or mandibular molar 4. Diagnosis must be Chronic Apical Periodontitis (CAP) with or without symptoms. 5. Intact, mature apices. 6. ASA I or II Exclusion Criteria: 1. Failure to meet any of the above 2. Previous NSRCT 3. Previous pulpotomy or pulpectomy 4. Suppurative apical periodontitis 5. Patients taking medications which can affect their pain rating or medications which effect their immune system ( such as glucocorticoids)
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT00223470