Clonidine-induced Spinal Acetylcholine Release: Normal Volunteers vs. Neuropathic Pain
CompletedPhase 2NCT00350532
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The purpose of this study is to compare the amount of acetylcholine release after a single injection of clonidine in normal volunteers and individuals with neuropathic pain.
Study details
- Official title
- Clonidine-induced Spinal Acetylcholine Release: Normal Volunteers vs. Neuropathic Pain
- Conditions
- Interventions
- Sponsor
- Wake Forest University Health Sciences
- Collaborators
- National Institute of Neurological Disorders and Stroke (NINDS)
- Start date
- 2004-09
- Primary completion
- 2008-03
- Sex
- All
- Age range
- from 18 Years
- Healthy volunteers
- true
- Results posted
- Yes, on ClinicalTrials.gov
- Countries
- United States
- Total sites listed
- 2
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Healthy adult volunteers * Patients with neuropathic pain Exclusion Criteria: * Pregnancy * Allergy to clonidine * Currently taking clonidine or other direct a2-adrenergic agonists * Taking cholinesterase inhibitors
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT00350532