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Augmented Cerebral Pain Processing in Chronic, Unexplained Pain: a fMRI Study

CompletedNCT00463177
View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

Chronic, unexplained pain symptoms are very common in all layers of the population, but it is largely unknown what causes them. This study examines the hypothesis that patients with these pain symptoms process pain abnormally in their brain. TO this aim, we compare patients and healthy people: they receive mild pain at their painful body region and at another location. Concurrently, we measure brain activity with brain scans (functional MRI scans). With our study results, we want to increase understanding of what causes chronic, unexplained pain symptoms, in order to find better methods of diagnosing and treating them.

Study details

Official title
Augmented Cerebral Pain Processing in Chronic, Unexplained Pain: a 3T Event-Related Functional MRI Study
Conditions
Sponsor
UMC Utrecht
Collaborators
K.F. Hein Foundation; Fonds Psychische Gezondheid
Start date
2007-03
Primary completion
2008-06
Sex
All
Age range
from 18 Years
Results posted
No results posted in this snapshot
Countries
Netherlands
Total sites listed
1

Eligibility criteria

Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Chronic limb pain \> 6 months * No known somatic cause Exclusion Criteria: * Chronic benzodiazepine use * Axis-I psychiatric co-morbidity * Contra-indications for MRI scanning (e.g. implanted pacemaker)

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT00463177