Opioid Rotation Versus Combination for Chronic Uncontrolled Cancer Pain
CompletedPhase 2NCT00478101
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
For cancer patients with inadequate pain relief, a switch to an alternative opioid is the preferred option for symptomatic improvement. However, multiple opioids are often simultaneously administered for anecdotal reasons. The present study isdesigned to assess the analgesic profiles of two different strategies in chronic cancer pain: the opioid rotation from oxycodone to transdermal fentanyl and the combination of oral oxycodone and transdermal fentanyl.
Study details
- Conditions
- Advanced Solid Cancers
- Interventions
- Drug: oxycodone fentanyl
- Sponsor
- Gachon University Gil Medical Center
- Start date
- 2006-02
- Sex
- All
- Age range
- from 19 Years
- Results posted
- No results posted in this snapshot
- Total sites listed
- 0
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Chronic Uncontrolled Pain That Required Stronger Opioid Therapy Than They Have Been Taking * Histologically Confirmed Solid Cancer * Aged Over 18 Years * Admitted in a Palliative Cancer Care Unit Exclusion Criteria: * Uspected to Have Narcotic Abuse, Clinically Relevant CO2 Retention or Had an Active Skin Disease * Inability to swallow oral medication, and impaired sensory or cognitive function * Patients who had an active infection, uncontrolled central nervous system involvement, or on antitumor therapy of any kind
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT00478101