Microneurography and Spinal Cord Stimulation in Chronic Visceral Pain

Brief summary (from the registry)

The purpose of this study is to assess the effect of the spinal cord stimulator (A small wire is surgically implanted under the skin. Low-level electrical signals are then transmitted through the lead to the spinal cord to alleviate pain. Using a magnetic remote control, the patients can turn the current on and off, or adjust the intensity.) on the autonomic nervous system (sympathetic and parasympathetic). Some studies support that the spinal cord stimulation suppresses or decreases sympathetic outflow (the sympathetic nervous system is the one that provide us with the "flight and fight response" and the parasympathetic nervous system is the one that works while we "sleep, rest and digest".). The sympathetic nervous system is important in blood pressure regulation also. However, there are not reports regarding the effect of the spinal cord stimulation on blood pressure regulation in chronic visceral pain patients. Most clinical trials are focus on the effect of the spinal cord stimulation on pain relief. We think we could use blood pressure, heart rate and special analysis of these signals and their relationship to other pain measurements to assess the effect of the spinal cord stimulation in an objective way.

Study details

Official title

Autonomic Function Testing and Spinal Cord Stimulation: Implications for Successful Therapy in Chronic Visceral Pain

Conditions

• Chronic Pain

Interventions

• Procedure: Autonomic Evaluation

Sponsor

Vanderbilt University Medical Center

Start date

2008-02

Primary completion

2009-01-23

Sex

All

Age range

from 18 Years to 65 Years

Healthy volunteers

true

Results posted

No results posted in this snapshot

Countries

United States

Total sites listed

1

Eligibility criteria