Proteomics of Cerebrospinal Fluid in Chronic Fatigue Syndrome

Inclusion Criteria: 1. Chronic Fatigue Syndrome 2. Fibromyalgia 3. Gulf War Illness 4. Multiple Chemical Sensitivity 5. Irritable Bowel Syndrome 6. Interstitial Cystitis Exclusion Criteria: 1. You do not want to have a lumbar puncture performed. 2. You have a severe physical impairment that does not permit lumbar puncture or completion of the remainder of the tests (e.g. severe scoliosis or curvature of the back). 3. You have a medical condition with symptoms similar to Chronic Fatigue Syndrome such as regional pain syndromes, reflex sympathetic dystrophy, morbid obesity, autoimmune / inflammatory diseases, cardiopulmonary disorders), neurological disorders (e.g. seizures, dementia, degenerative disorders), uncontrolled endocrine or allergic diseases or, cancer. 4. You have a severe psychiatric illness such as schizophrenia, substance abuse, major depression with previous suicidal attempts, gestures or ideas about committing suicide. 5. You are mentally retarded or cannot understand this informed consent, cannot provide absolute willingness to have a lumbar puncture as part of this study, or are unable to complete the questionnaires and other studies that are part of this research project 6. You are in jail or prison. 7. You are pregnant. 8. You smoke more than 5 cigarettes per day. You will be allowed to taper your smoking before your participation in the actual study visit. This is an excellent opportunity to ask about our Smoking Cessation Programs. 9. You drink or eat caffeine containing products with more than the equivalent of 2 cups of coffee. You will be allowed to taper your caffeine intake before the study visit. 10. You have used narcotics or other illegal medications for more than 3 months. These will be discussed with Dr. Baraniuk. 11. You have a positive HIV test, or blood, liver or kidney tests that are abnormal. 12. You are participating only so you can be paid for taking part in this spinal tap study.