Efficacy of Antidepressants in Chronic Back Pain
CompletedPhase 2NCT00964886
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
This 12 week placebo controlled clinical trial tests the individual and combined effects of an antidepressant medication and cognitive behavioral therapy for chronic back pain.
Study details
- Official title
- Efficacy of Antidepressants in Chronic Back Pain
- Conditions
- Interventions
- Behavioral: cognitive behavioral therapy
- Drug: desipramine hydrochloride
- Behavioral: cognitive behavioral therapy
- Drug: benztropine mesylate 0.125 mg daily
- Drug: desipramine hydrochloride
- Sponsor
- VA Office of Research and Development
- Collaborators
- University of California, San Diego
- Start date
- 2010-01
- Primary completion
- 2014-12
- Sex
- All
- Age range
- from 18 Years to 70 Years
- Results posted
- Yes, on ClinicalTrials.gov
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Chronic back pain (daily pain for \> 6 months) Exclusion Criteria: * Major medical conditions which might contraindicate antidepressant treatment
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT00964886