Lidocaine on Manifestations of Fibromyalgia
CompletedPhase 1NCT00991848
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Background and Objectives: Fibromyalgia is a pain syndrome characterized by numerous manifestations. The objective of this study was to evaluate the effect of the combination of intravenous lidocaine and amitriptyline on the manifestations of fibromyalgia. Methods: A prospective, randomized, double-blind, comparative study was conducted. All patient received 25 mg amitriptyline. Patients of group 1 (n = 15) received 125 mL 0.9% saline, and patients of group 2 (n = 15) received 240 mg lidocaine in 125 mL 0.9% saline once a week for 4 weeks. Manifestations were recorded before and 4 weeks after treatment. Pain intensity was rated on a verbal numerical scale.
Study details
- Official title
- Effect of Intravenous Lidocaine on Manifestations of Fibromyalgia
- Conditions
- Interventions
- Sponsor
- Federal University of São Paulo
- Start date
- 2005-01
- Primary completion
- 2007-07
- Sex
- All
- Age range
- from 18 Years to 60 Years
- Results posted
- No results posted in this snapshot
- Countries
- Brazil
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * pain in the four quadrants of the body for at least 3 months * sleep disorders * fatigue * subjective edema * depression * paresthesia. Exclusion Criteria: * alterations in thyroid * rheumatological * renal and hepatic function * trauma * rheumatic, neuromuscular or psychiatric disease * infectious arthropathy * other pain syndromes * drug hypersensitivity * pregnancy
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT00991848