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Nerve Growth Factor in Chronic Pancreatitis

CompletedNCT01255917
View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

This study is to understand the role of nerve growth factor(NGF) and other cytokines in the pancreatic fluid of patients with chronic pancreatitis. Hypothesis: 1. Pain does not correlate with changes in the PD morphology suggesting that pain in CP is not only a mechanical problem 2. Pain in CP correlates better with the levels of NGF in the pancreatic juice. NGF is variably expressed in different morphological stages of CP and regulates the sensitivity of the peptidergic nociceptors and is upregulated in pancreatic inflammation.

Study details

Official title
Nerve Growth Factor in Chronic Pancreatitis
Sponsor
Virginia Commonwealth University
Collaborators
Stanford University
Start date
2008-02
Primary completion
2011-08
Sex
All
Age range
from 18 Years to 70 Years
Results posted
No results posted in this snapshot
Countries
United States
Total sites listed
1

Eligibility criteria

Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Patients with established CP and none of the exclusion criteria mention below. Exclusion Criteria: * Failure to obtain consent. * Any comorbid condition with expected survival \< 1 year. * Patients with pacemaker, implanted metallic prosthesis or other contraindications to do MRCP. * Patients \< 18 years of age at time of consent

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT01255917