The Impact of Omega-3 Fatty Acid Supplements on Fibromyalgia Symptoms

Inclusion Criteria: * Women aged 18-65. * A diagnosis of FM according to the American College of Rheumatology classification criteria(Wolfe et al., 1990) * Negative urine pregnancy test at enrolment and willingness not to become pregnant for the duration of the study. * Pain levels of at least 4 on 10-cm VAS at the time of recruitment. * Ability to communicate in English or in French. * Willing to sign an informed consent. * If the patient is taking medication or natural health product (excluding omega-3 containing products) to treat fibromyalgia, she must be on a stable regimen for a minimum of two weeks before recruitment and be willing to keep this stable medication or natural health product regimen throughout the study period. * If the patient is using other therapies to treat fibromyalgia such as TENS, acupuncture, exercise, psychotherapy, massage, physiotherapy, etc, she must be doing so for a minimum of two weeks before recruitment and be willing to continue those therapies throughout the study period. Exclusion Criteria: * Use of anticoagulants (Coumadin® or Plavix®), having a bleeding disorder or being scheduled for a surgical procedure. This is because omega-3 fatty acids can prolong bleeding time, although doses we propose to use are safe (see Risks section) * Allergy to fish, olive oil, medium chain triglycerides, lemon, green tea, vitamin E or tylenol * Past (within the last year) or present specific dietary supplementation with omega-3 fish oil or other natural health products containing omega-3 fatty acids (e.g. flax seed oil, krill oil, etc) or regularly eating more than two fatty fish meals/week (salmon, mackerel, sardine, flounder, herring, or any other fish considered to have a high level of omega-3 fatty acids). * Patient enrolled in another research study involving any treatment. * Patient engaged in active litigation * Regular use of recreational drugs * Alcohol consumption \> 10 units/week * Morbidly obese patients * Pregnancy or breastfeeding * Uncontrolled major medical conditions. Neurological problems. Current psychiatric condition. Chronic pain condition other than FM.