The Immune and Clinical Impacts of Vitamin D in Patients With Chronic Musculo-skeletal Pain

Brief summary (from the registry)

Vitamin D3 is produced in the skin following exposure to UVB light from the sun or artificial sources, and occurs naturally in a small range of foods.More recently, several reports underlined the impact of vitamin D on the prevalence and consequences of inadequate vitamin D intake and the research supporting its benefits for alleviating chronic musculoskeletal pain and fatigue syndromes in outpatients. Experts have recommended that vitamin D inadequacy should be addressed in all patients with bone or joint pain, myalgia, fibromyalgia, or chronic fatigue syndrome. It appears that soothing the daily musculoskeletal pain by supplementation of vitamin D may be a simple, well tolerated, and cost-effective modality. Aim of study: To study the potential therapeutic effects of vitamin D supplementation on patients with persistent musculo-skeletal pain. Clinicalparameters, visual analog score,short form McGill Pain Questionnaire,patient global perceived effect, quality of life assessed by SF-36 Questionnaire and laboratory parameters, the levels of 25 OH-Vitamin D, CRP, IL-6, IL-8, TNF and prostaglandin E will be assessed.

Study details

Official title

The Immune and Clinical Impacts of Vitamin D in Patients With Chronic Musculo-skeletal Pain

Conditions

• Vitamin D Deficiency
• Chronic Pain Syndrome
• Inflammatory Response

Interventions

• Drug: vitamin D

Sponsor

Meir Medical Center

Start date

2011-09

Primary completion

2012-12

Sex

All

Age range

from 18 Years to 80 Years

Results posted

No results posted in this snapshot

Countries

Israel

Total sites listed

1

Eligibility criteria