Safety Study of Renal Function in Patients With Chronic Kidney Failure Taking Lumiracoxib or Diclofenac for Arthralgia
TerminatedPhase 2NCT01481610
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The purpose of this study is to determine whether the use of lumiracoxib in this particular population is associated with a decrease in glomerular filtration rate (GFR) compared to diclofenac; and to compare the magnitude of such impairment, if any, associated with use of lumiracoxib and diclofenac.
Study details
- Official title
- Comparison of the Effects on Renal Function of Lumiracoxib and Diclofenac in Patients With Chronic Kidney Failure K/DOQI Stage III at the HCSAE PEMEX
- Conditions
- Kidney Failure, Chronic
- Arthralgia
- Interventions
- Drug: Lumiracoxib
- Drug: Diclofenac
- Sponsor
- Hospital Central Sur de Pemex
- Start date
- 2012-01
- Primary completion
- 2012-11
- Sex
- All
- Age range
- from 60 Years
- Results posted
- No results posted in this snapshot
- Countries
- Mexico
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * chronic joint pain, requiring analgesia * pre-existing chronic kidney injury, stage K/DOQI III (GFR 30 - 59 ml/min) * in a stable phase of CKD (i.e. not AKI, not hospitalized) * without contraindications for NSAID therapy * who have signed an informed consent Exclusion Criteria: * having received any NSAID 2 weeks prior to study start * history of / actual PUD * patients with ESRD (K/DOQI IV, V or replacement therapy) * history of hypersensitivity or allergies to any of the treatments * history of / actual GI bleeding * with impaired liver function tests * using ACEI / ARB
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT01481610