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Effects of Transcranial Direct Current Stimulation (tDCS) in Chronic Corneal Pain

CompletedNot applicableNCT01575002
View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

In this study the investigators aim to examine the effects of Transcranial Direct Current Stimulation (tDCS) on pain levels as well as the changes in cognitive (thought) processing in individuals with chronic pain of the cornea -- and also compared with healthy controls.

Study details

Official title
Neural Correlates of Pain-related Cognitive Processing in Chronic Pain of the Cornea: an ERP and Electrical Stimulation Study.
Conditions
Sponsor
Spaulding Rehabilitation Hospital
Start date
2012-01
Primary completion
2015-09
Sex
All
Age range
from 18 Years to 65 Years
Healthy volunteers
true
Results posted
No results posted in this snapshot
Countries
United States
Total sites listed
1

Eligibility criteria

Show eligibility criteria (verbatim from the registry)
Inclusion Criteria (for all subjects): 1. Provide informed consent to participate in the study; 2. 18 to 65 years old; Additional Inclusion Criteria for Subjects with Chronic Corneal Pain: 1. Corneal pain for six months or more; 2. Referral from a corneal specialist (Dr. Perry Rosenthal) with refractoriness to conventional ophthalmologic treatments for corneal pain such as local topical medications and soft bandage contact lenses; 3. Report a Visual Analogue Scale (VAS) for pain of 4 or greater in the previous 3 weeks; Exclusion Criteria (for all subjects): 1. History of alcohol or substance abuse within the last 6 months as self-reported; 2. Diagnosis of any neurological diseases (such as epilepsy); 3. Episodes of seizures within the last 6 months; 4. Unexplained loss of consciousness 5. Use of carbamazepine or neuropsychotropic drugs 6. Contraindications to tDCS * Metal in the head * Implanted brain medical devices 7. Pregnant at time of enrollment

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT01575002