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Brain Imaging Study of Acupuncture in Chronic Low Back Pain

CompletedNot applicableNCT01614639
View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

We are doing this research study to learn about how acupuncture treatment works. This study is being done to look at changes in the brain, NOT to treat pain. We want to learn about brain activity during acupuncture. We will look at brain activity when a heating device touches the skin of a subject before and after the subject has acupuncture, to see what changes.

Study details

Official title
A Physiological fMRI Study of Acupuncture and Perceptions of Pain in Chronic Low Back Pain Patients.
Sponsor
Brigham and Women's Hospital
Collaborators
Massachusetts General Hospital; National Center for Complementary and Integrative Health (NCCIH)
Start date
2012-01
Primary completion
2017-05
Sex
All
Age range
from 18 Years to 60 Years
Healthy volunteers
true
Results posted
No results posted in this snapshot
Countries
United States
Total sites listed
1

Eligibility criteria

Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Meet the Classification Criteria of chronic LBP (having low back pain for more than 6 months), as determined by the referring physician * At least 4/10 clinical pain on the 10-point LBP intensity scale on average during the past two weeks prior to enrollment * At least a 10th grade English-reading level; English can be a second language provided that the patients feel they understand all the questions used in the assessment measures * Must have had a prior evaluation of their low back pain by a health care provider, which may include radiographic studies. Documentation of this evaluation will be obtained from the subject's medical record Exclusion Criteria: * Specific causes of back pain (e.g., cancer, fractures, spinal stenosis, infections) * Radicular pain extending below the knee * Complicated back problems (e.g., prior back surgery, medicolegal issues) * Possible contraindications for acupuncture (e.g., coagulation disorders, cardiac pacemakers, pregnancy, seizure disorder), and conditions that might confound treatment effects or interpretation of results (e.g., severe fibromyalgia, rheumatoid arthritis) * Conditions making study participation difficult (e.g., paralysis, psychoses, or other severe psychological problems as per the judgment of a study investigator and/or a T score \> 60 on the psychological measures assessed during Session 1) * Prior acupuncture treatment for back pain; 1 year minimum wait for any condition other condition. * Active substance abuse disorder in the past two years, as determined by subject self-report. * The intent to undergo surgery during the time of involvement in the study. * History of cardiac, respiratory, or nervous system disease that, in the investigator's judgment, precludes participation in the study because of a heightened potential for adverse outcome. For example: asthma or claustrophobia. * Presence of any contraindications to MRI scanning. For example: cardiac pacemaker, metal implants, fear of closed spaces, pregnancy. * Unresolved legal/disability/workers compensation claims in connection with low back. * Instability of pain ratings in Session 2 or Session 3. * Use of more than 60 mg prescription opioids or steroids for pain.

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT01614639