The Role of Intravenous (IV) Lidocaine in the Management of Chronic Neuropathic Pain of Peripheral Nerve Origin
CompletedNot applicableNCT01669967
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Brief summary (from the registry)
Pain as a result of nerve injury (neuropathic pain) is a particularly severe form of chronic pain. Common examples of neuropathic pain are pain due to diabetes and shingles. There is good evidence that an intravenous infusion of lidocaine (local anesthetic) is useful for the management of neuropathic pain in the short term - up to six hours.
Study details
- Official title
- The Role of Intravenous (IV) Lidocaine in the Management of Chronic Neuropathic Pain of Peripheral Nerve Origin
- Conditions
- Interventions
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
- Start date
- 2011-09
- Primary completion
- 2015-12
- Sex
- All
- Age range
- from 18 Years to 80 Years
- Results posted
- No results posted in this snapshot
- Countries
- Canada
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Chronic neuropathic pain due to diabetes mellitus or herpes zoster and a score of 4/10 or greater on the DN4 questionnaire. * Moderate to severe pain as defined by screening average pain intensity of 5 or greater on a 0-10 numerical rating scale. * Neuropathic pain duration of at least 6 months. Exclusion Criteria: * Presence of clinically significant cardiac disease. * Poorly controlled seizure disorder. * Significant psychiatric disorder. * History of allergy to lidocaine or any other amide local anesthetic * History of allergy to diphenhydramine. * Prior treatment with a local anesthetic infusion. * Neuropathic pain due to cancer or complex regional pain syndrome * Language barrier or cognitive impairment that would preclude understanding of the study and filling out of questionnaires * Lack of a driver to transport the patient to and from the pain clinic.
Canadian sites (1)
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT01669967