Effects of Transcranial Direct Current Stimulation (tDCS) on Neuropathic Symptoms Following Burn Injury
CompletedNot applicableNCT01795079
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The purpose of this study is to see the effects of transcranial direct current stimulation (tDCS) on the pain and itching associated with burn injury. This study is part of the Boston-Harvard Burn Model System. The investigators hypothesize that there will be a decrease in pain levels with active stimulation, when compared to sham stimulation, using a 3 week stimulation schedule- 2 weeks of stimulation (10 consecutive days) followed by 1 week of stimulation (5 consecutive days) after three follow up visits at 2, 4 and 8 weeks after initial course of stimulation. The subject will also have follow ups at 2, 4 and 8 weeks after the second course of stimulation. If a subject receives sham during the experiment, he/she may enroll in an open-label portion of the study and receive 10 days of active stimulation.
Study details
- Official title
- Boston-Harvard Burn Injury Model System: Cortical Modulation With Transcranial Direct Current Stimulation (tDCS) for Neuropathic Symptoms Following Burn Injury
- Conditions
- Burn Injury
- Chronic Pain
- Pruritus
- Itching
- Sponsor
- Spaulding Rehabilitation Hospital
- Collaborators
- U.S. Department of Education
- Start date
- 2013-01
- Primary completion
- 2019-07
- Sex
- All
- Age range
- from 18 Years
- Results posted
- Yes, on ClinicalTrials.gov
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Providing informed consent to participate in the study * Age 18 or older * Burn injury with pain and/or itch that is moderate to severe * Burn injury occurring at least 3 weeks prior to enrollment Exclusion Criteria: * Subjects with burns in scalp in the area of electrode placement * Psychiatric disorders that have led to hospitalization within the past 6 months or signs of suicidality * Learning disorders that may prevent patient's ability to complete assessments * Unstable conditions preventing travel to study site * Current use of any of the following anti-epileptic medications or dopaminergic medications known to reduce or inhibit the benefits of tDCS treatment: carbamazepine, oxcarbazepine, phenytoin * Contraindications to tDCS including implanted metal plates in the head or implanted brain medical devices * Pregnancy at time of enrollment * History of other neurological conditions associated with structural anatomical changes (i.e. stroke, brain injury, Parkinson's)
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT01795079