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Prediction of Inter-individual Differences in the Response to Morphine Versus Milnacipran in Patients With Sciatica

Unknown statusPhase 2NCT01914042
View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

Clinical, psychophysical, behavioral or genetic factor will predict the response to opioid treatment in patients with chronic neuropathic pain.

Study details

Official title
Prediction of Inter-individual Differences in the Response to Morphine by Psychophysical Assessment of Pain Enhancing and Inhibiting Mechanisms in Patients With Chronic Neuropathic Pain
Sponsor
Rambam Health Care Campus
Start date
2013-07
Primary completion
2019-07
Sex
All
Age range
from 18 Years to 75 Years
Results posted
No results posted in this snapshot
Countries
Israel
Total sites listed
1

Eligibility criteria

Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: 1. Patients with moderate to severe chronic neuropathic pain or patients with radiculitis between 18 and 75 years of age. 2. Candidates for chronic opioid therapy for nonmalignant pain as determined by treating physician. 3. Patients treated with non-opioid analgetics, anti- inflammatory drugs or low opioid dosage (\< 30 mg of oral morphine-equivalents per day). 4. Ability to understand the purpose and instructions of the study and to sign an informed consent. \- Exclusion Criteria: 1.Diabetic Neuropathy 2.Pain in upper limbs 3.Receiving anti- depressants and/or anticonvulsants 4.Pregnant women 5.Inability to comply with study protocol. 6.Allergy to Opioids 7.A diagnosis of Raynaud's Syndrome 8.History of substance abuse \-

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT01914042