Comprehensive Pain Programme to Determine Mechanism of Transition of Acute to Chronic Postsurgical Pain
CompletedNot applicableNCT02025153
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
To determine whether central sensitization is a mechanism of CPSP (chronic postsurgical pain) in women who will develop CPSP compared to women with no CPSP after hysterectomy. This mechanism is illustrated by a higher pain score in experimental pain models such as tonic heat stimulation, increased evoked mechanical temporal summation and increased wound hyperalgesia.
Study details
- Official title
- Comprehensive Pain Programme to Determine Mechanism of Transition of Acute to Chronic Postsurgical Pain- Functional Brain Imaging, Quantitative Sensory Testing, Psychological and Genetic Screening: Prospective Cohort Study
- Conditions
- Chronic Pain
- Anaesthesia
- Genetics Predisposition
- Interventions
- Other: pain testing
- Sponsor
- KK Women's and Children's Hospital
- Start date
- 2013-09
- Primary completion
- 2017-06
- Sex
- Female
- Age range
- from 21 Years to 70 Years
- Results posted
- No results posted in this snapshot
- Countries
- Singapore
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Anthropometric profile within the following range: age 21-70 yr, American Society of Anesthesiology status I and II women * Benign condition such as fibroids or adenomyosis * Abdominal or laparoscopic hysterectomy Exclusion Criteria: * Vaginal hysterectomy * being pelvic pain * Failure to adequately determine tonic heat stimulation and mechanical temporal summation * History of drug dependence or recreational drug use * Allergy to any study drugs
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT02025153