Remifentanil vs Fentanyl During Cardiac Surgery and Chronic Thoracic Pain
CompletedPhase 4NCT02031016
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
This study will investigate the influence of intra-operative use of remifentanil versus fentanyl on the percentage of patients with chronic thoracic after cardiac surgery via sternotomy. Secondary quantitative sensory testing is performed to determine thermal and electrical detection and pain threshold and the difference in pain variability scoring. Postoperative pain scores, analgesic use, genetic variances and costs are measured.
Study details
- Official title
- A Randomised Clinical Trial Evaluating the Effect of Remifentanil vs Fentanyl During Cardiac Surgery on the Incidence of Chronic Thoracic Pain
- Conditions
- Chronic Pain
- Sternotomy
- Remifentanil
- Fentanyl
- Interventions
- Sponsor
- St. Antonius Hospital
- Start date
- 2014-02
- Primary completion
- 2016-04
- Sex
- All
- Age range
- from 18 Years to 85 Years
- Results posted
- No results posted in this snapshot
- Countries
- Netherlands
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Patients undergoing cardiac surgery via sternotomy (Coronary artery bypass graft (CABG) and/or valve replacement) * Patients admitted to the ICU or PACU in the St. Antonius hospital * Patients between 18 and 85 years old * Patients weighing between 45 and 140 kg * Written informed consent Exclusion Criteria: * Pregnancy/ breastfeeding * Language barrier * History of drug abuse * Neurologic condition such as peripheral neuropathy * Known remifentanil, fentanyl, morphine or paracetamol allergy * Body Mass Index (BMI) \> 35 kg/m2 * Prior cardiac surgery (re-operations); * Patients with chronic pain conditions.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT02031016