Efficacy of Intrathecal Oxytocin in Patients With Neuropathic Pain
TerminatedPhase 2NCT02100956
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The purpose of the study is to determine the effect of oxytocin given into the spinal fluid on pain and areas and intensity of hyperalgesia and allodynia in patients with chronic neuropathic pain.
Study details
- Official title
- Efficacy of Intrathecal Oxytocin in Patients With Neuropathic Pain
- Conditions
- Interventions
- Drug: oxytocin 100 micrograms
- Drug: Normal Saline (preservative free)
- Sponsor
- Wake Forest University Health Sciences
- Start date
- 2014-06-19
- Primary completion
- 2022-10-10
- Sex
- All
- Age range
- from 18 Years to 70 Years
- Results posted
- Yes, on ClinicalTrials.gov
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Weight \< or equal to 240 pounds * Neuropathic pain for \> 6 months: with primary pain area below the umbilicus Exclusion Criteria: * Hypersensitivity, allergy, or significant reaction to any ingredient of the study drug or lidocaine * Any disease, diagnosis, or condition (medical or surgical) that, in the opinion of the Principal Investigator, would place the subject at increased risk (active gynecologic disease in which increased tone would be detrimental e.g., uterine fibroids with ongoing bleeding), compromise the subject's compliance with study procedures, or compromise the quality of the data * Pregnancy * spinal cord stimulators, chronic intrathecal drug therapy, or oral opioid treatment for \> 3 months at a current dose of \> 100 milligram (mg) morphine per day or equivalent.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT02100956