Pupil Response in Patients on Opioids.
CompletedNCT02247024
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Evaluation of pupillary reflex in patients on high-dose opioids. Clinical assessment of pain intensity, sedation score, and other side effects of opioids. Measurements of the concentration of opioids and their active metabolites in blood.
Study details
- Official title
- Dynamic Assessment of Pupillary Reflex in Patients on High-dose Opioids
- Conditions
- Chronic Pain
- Impaired Pupillary Reflex
- Opioid-Related Disorders
- Sponsor
- Oslo University Hospital
- Start date
- 2015-01
- Primary completion
- 2018-08
- Sex
- All
- Age range
- from 18 Years
- Results posted
- No results posted in this snapshot
- Countries
- Norway
- Total sites listed
- 2
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * In-patients and out-patients at Oslo University Hospital with cancer pain who have use opioids (morphine, oxycodone, fentanyl or methadone or a combination of these drugs) at least for periods of 4 weeks, and use opioids corresponding to at least 60 mg oral morphine equivalents pr day Exclusion Criteria: * Patients who have undergone eye-surgery that may influence pupillary reflexes * Patients on local medication that may influence pupillary reflexes * Patients with amyloidosis, multiple sclerosis, Horner's syndrome, or ongoing migraine attack * Patients with brain tumor
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT02247024