Bifidobacteria In Children With Abdominal Pain-Associated Functional Gastrointestinal Disorders

Brief summary (from the registry)

Abdominal pain (AP)-associated functional gastrointestinal disorders (FGIDs), particularly Irritable Bowel Syndrome (IBS) and Functional Dyspepsia (FD), are common in pediatrics, and no safe and effective treatment is available. Although probiotics have shown promising results in adults, few studies have been published in children. The Bifidobacterium Infantis, Bifidobacterium Breve and Bifidobacterium Longum are the most important beneficial bacteria in children and represent 95% of the total bacterial population in the intestine of breastfed infant. Objectives: 1) To evaluate the effect of oral administration of a mixture of Bifidobacteria on the improvement of frequency and intensity of AP in children with FD and IBS. 2) To evaluate the effect of oral administration of a mixture of Bifidobacteria on quality of life in children with FD and IBS.

Study details

Official title

A Multicentre, Randomised, Double-Blind, Placebo Controlled, Crossover Trial On The Efficacy Of A Mixture Of Three Bifidobacteria In Children With Abdominal Pain-Associated Functional Gastrointestinal Disorders

Conditions

• Irritable Bowel Syndrome
• Dyspepsia Chronic

Interventions

• Drug: Mixture of three Bifidobacteria

Sponsor

Federico II University

Start date

2013-12

Primary completion

2015-07

Sex

All

Age range

from 4 Years to 18 Years

Results posted

No results posted in this snapshot

Countries

Italy

Total sites listed

1

Eligibility criteria