Efficacy of Opioid-free Anesthesia in Reducing Postoperative Pain in Chronic Pain Patients Undergoing Spinal Surgery
Unknown statusPhase 3NCT02752477
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Brief summary (from the registry)
The objective of this trial is to determine whether an opioid-free general anesthetic (OFA) technique utilizing ketamine, dexmedetomidine, and lidocaine infusions can help reduce postoperative pain in opiate-dependent chronic pain patients (CPPs) undergoing spine surgery when compared with traditional opioid-containing techniques. It is expected that this OFA regimen will have a measurable reduction on postoperative opioid consumption and pain scores in CPPs.
Study details
- Official title
- Efficacy of Opioid-free Anesthesia in Reducing Postoperative Pain in Chronic Pain Patients Undergoing Spinal Surgery: A Pilot Study
- Conditions
- Interventions
- Drug: Opioid-free general anesthetic
- Drug: Traditional general anesthetic
- Sponsor
- Ben Lim
- Organization
- University of Saskatchewan
- Start date
- 2016-08-02
- Primary completion
- 2020-09
- Sex
- All
- Age range
- from 18 Years
- Results posted
- No results posted in this snapshot
- Countries
- Canada
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Chronic pain \> 6 months, opiate-using patients scheduled for thoracic or lumbar spinal surgery Exclusion Criteria: * Pregnant or breastfeeding women, significant hepatic, renal or cardiac disease, allergy to any of the study drugs, inability to consent, respond to pain assessments or use the patient controlled analgesia device
Canadian sites (1)
| Facility | City | Province |
|---|---|---|
| Royal University Hospital | Saskatoon | Saskatchewan |
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT02752477