Anesthesia for Pain After Ankle Fracture Surgery
CompletedPhase 4NCT02950558
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
This pilot study will test the hypothesis that prolonged regional peripheral nerve block will reduce development of chronic pain in patients undergoing surgery for ankle fracture compared to standard of care. Subjects will be followed for one year.
Study details
- Official title
- Pilot Study: Extended Regional Anesthesia to Prevent Chronic Pain After Ankle Fracture Surgery
- Conditions
- Chronic Pain
- Ankle Fracture Surgery
- Regional Anesthesia
- Interventions
- Sponsor
- University of Cincinnati
- Start date
- 2018-05-29
- Primary completion
- 2019-11-14
- Sex
- All
- Age range
- from 18 Years to 65 Years
- Results posted
- Yes, on ClinicalTrials.gov
- Countries
- United States
- Total sites listed
- 2
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Referred for surgery for open reduction and internal fixation for ankle fracture Exclusion Criteria: * Unable to give informed consent in English * Unable to complete surveys in English * Unable to understand instructions for using pump in English * Unavailable for followup * Polytrauma; undergoing other surgeries or having other orthopedic injuries related to the precipitating cause of the ankle fracture * Infection * Peripheral vascular disease * Diabetes * Currently undergoing chemotherapy * Pregnancy * Currently lactating * Heart disease or heart rhythm disorder or taking anti-arrhythmic drugs * Severe renal impairment (Class 3 or worse kidney disease) * Liver disease (cirrhosis or liver failure) * Prior allergic reaction to any type of local anesthetic * Taking therapeutic doses of anti-coagulants or anti-platelet therapy (prophylactic doses started because of hospital admission are not an exclusion) * Currently taking antidepressants or other psychiatric medications * Single shot local nerve block prior to surgery was ineffective * Selected for neuraxial anesthesia rather than general anesthesia for the open reduction surgery * Already receiving chronic analgesic therapy for a separate chronic pain condition
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT02950558