The Effects of Apomorphine on Experimental and Clinical Pain in Patients With Chronic Radicular Pain
CompletedPhase 4NCT02969629
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The study aimed to explore the effect of the dopamine agonist apomorphine on spontaneous pain intensity and evoked cold clinical and experimental pain in patients with lumbar radicular neuropathic pain (NP). Patients received either apomorphine or placebo in a randomized double-blinded manner.
Study details
- Official title
- The Effects of the Dopamine Agonist (Apomorphine) on Experimental and Clinical Pain in Patients With Chronic Radicular Pain: a Randomized, Double-blind, Placebo-controlled, Cross-over Study
- Conditions
- Interventions
- Drug: Apomorphine
- Drug: Normal Saline
- Sponsor
- Rambam Health Care Campus
- Start date
- 2012-12
- Primary completion
- 2014-12
- Sex
- All
- Age range
- from 18 Years
- Results posted
- No results posted in this snapshot
- Countries
- Israel
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: 1. Presence of radicular pain for at least 3 months; 2. Average pain level during the last week prior to enrollment \> 40 (0-100); 3. No use of a new analgesic drug within 30 days prior to entry to the study and 4. Adults who were capable of understanding the purpose and instructions of the study and signing an informed consent. Exclusion Criteria: 1. Pregnancy or breastfeeding; 2. Presence of Parkinson's disease or any other extra-pyramidal diseases; 3. History of allergy to the investigational drugs: Apomorphine or Domperidone; 4. History of polyneuropathy and 5. Respiratory depression, dementia, psychotic diseases or hepatic insufficiency
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT02969629