The Effects of Water Temperature on the Cold Pressor Test

Brief summary (from the registry)

This current study is intended to be completed under the umbrella of the current GHUCCTS IRB- approved study "Opioid-Induced Hyperalgesia In Prescription Opioid Abusers: Effects of Pregabalin" (Lyrica study) (PRO00000669). In this proposed study, 10 healthy male, 10 healthy female participants and 5 male, 5 female OIH participants (from the parent Lyrica study), who are prescription opioid abusers with chronic pain currently taking Suboxone, will be asked to take the cold pressor test at 1, 5, and 9 degrees Celsius and to report the time at which pain has completely gone away following each test. The purpose of this study is to examine how the water temperature of the cold pressure test might affect the participants' response (i.e., the participants pain threshold and pain tolerance) and to see if there is a difference in how each participation group is affected.

Study details

Official title

The Effects of Water Temperature on the Cold Pressor Test in Patients With Opioid-Induced Hyperalgesia in Comparison to Healthy Controls

Conditions

• Chronic Pain

Interventions

• Other: Cold pressor test

Sponsor

Georgetown University

Start date

2015-05-01

Primary completion

2017-03-31

Sex

All

Age range

from 21 Years to 65 Years

Healthy volunteers

true

Results posted

No results posted in this snapshot

Countries

United States

Total sites listed

1

Eligibility criteria