Efficacy of Laser Debridement on Pain and Bacterial Load in Chronic Wounds

Inclusion Criteria: * Aged eighteen years or older * Having a chronic wound (as defined by lack of at least 50% reduction in wound surface area over a period of four weeks) * No clinical evidence of active wound bed infection * No exposure of any vital structure (i.e., tendon, bone, vessel) * Has signed the informed consent form prior to any study protocol related procedure * Willing and able to adhere to protocol requirements Exclusion Criteria: * Any unstable medical condition that would cause the study treatment to be detrimental to the subject, as judged by the Principle Investigator * Documented medical history of significant cardiac, pulmonary, gastrointestinal, endocrine (other than Diabetes Mellitus type 1 or 2), metabolic, neurological, hepatic or nephrologic disease would impede the subject's participation, as judged by the Principle Investigator * Documented medical history of immunosuppression, immune deficiency disorder, or currently using immunosuppressive medications * Having clinical presentation of active osteomyelitis * Pregnancy or lactation * Participation in another clinical study involving ulcers within thirty days prior to enrollment