Acupressure for Fatigue in Systemic Lupus Erythematosus
TerminatedNot applicableNCT03200548
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by involvement of multiple organs with a female to male ratio of 12:1 with the highest incidence reported in women of child bearing age (15-44 years). In general, advances in diagnosis and management have led to significant improvements in outcomes. However, fatigue remains a challenging and prevalent issue for SLE patients. The investigators aim to determine the feasibility of recruiting and conducting acupressure in fatigued persons with lupus; to explore the effect of two distinct acupressure formulas (relaxing and stimulating) plus usual care versus sham acupressure plus usual care and usual care alone on severity and impact of chronic fatigue (as measured by the Brief Fatigue Inventory) as well as quality of life, sleep and pain.
Study details
- Official title
- Acupressure for Persistent Fatigue in Systemic Lupus Erythematosus Patients
- Conditions
- Fatigue
- Lupus Erythematosus, Systemic
- Pain, Chronic
- Quality of Life
- Sleep
- Interventions
- Behavioral: Relaxing acupressure plus usual care
- Behavioral: Usual care
- Behavioral: Stimulating acupressure plus usual care
- Behavioral: Sham acupressure plus usual care
- Sponsor
- Suzanna Zick
- Collaborators
- University of Michigan
- Organization
- University of Michigan
- Start date
- 2017-08-14
- Primary completion
- 2019-07-19
- Sex
- Female
- Age range
- from 18 Years
- Healthy volunteers
- true
- Results posted
- Yes, on ClinicalTrials.gov
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Report chronic (\> 3 months) clinically relevant fatigue, defined as a score of ≥ 4 on the Brief Fatigue Inventory (BFI) * Have inactive disease, defined as SELENA SLEDAI ≤ 4 AND/OR no hospitalization or addition or increase in dose of corticosteroids, immunosuppressive agents, or antimalarial medications in the last 30 days. * Have no commonly recognized medical explanations for fatigue (a history of cancer in the previous 5 years -except certain low risk cancer, unstable thyroid disease, moderate to severe chronic kidney disease, moderate to severe anemia) * Are taking stable doses of anti-malarial therapy (hydroxychloroquine, quinacrine) for at least 6 months. * Baseline glucocorticoid dose equivalent of ≤ 10 mg prednisone. * No other planned intervention for fatigue other than current stable medication regimen Exclusion Criteria: * Pregnant or breast feeding * Have a diagnosis of untreated mood disorder, e.g., bipolar or major depressive disorder * Have an initiation, a cessation or change of treatment of any chronic medications, dietary supplements, behavioral therapy, physical therapy etc., or any planned change of medications, supplements or therapies during the study * Acupuncture or acupressure receipt in past year
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT03200548