Treatment of Chronic Pain With Cannabidiol (CBD) and Delta-9-tetrahydrocannabinol (THC)
CompletedEarly phase 1NCT03215940
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
This is a study comparing the effects of Delta-9-Tetrahydrocannabinol (THC) versus Cannabidiol (CBD) versus a placebo on chronic non-cancer pain.
Study details
- Official title
- Treatment of Chronic Pain With Cannabidiol (CBD) and Delta-9-tetrahydrocannabinol (THC): Effectiveness, Side Effects and Neurobiological Changes
- Conditions
- Interventions
- Drug: Delta-9-Tetrahydrocannabinol
- Drug: Cannabidiol
- Drug: Placebos
- Sponsor
- University of Utah
- Start date
- 2018-02-01
- Primary completion
- 2024-12-01
- Sex
- All
- Age range
- from 18 Years to 50 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion criteria: 1. Age between 18-50 yrs. 2. History of cannabis use. 3. Chronic musculoskeletal and joint pain for at least 3 months or longer. 4. Participants must live within a 60 mile radius of Salt Lake City, Utah to be eligible. Exclusion criteria: 1. Current or past neurological illness. 2. Substance abuse or dependence within the prior 60 days. 3. Contraindication to brain MRI. 4. Type I and type II diabetes. 5. Unstable medical conditions. 6. Consumption of more than 2 drinks of alcohol per night. 7. Current pregnancy or planning to become pregnant or breastfeeding 8. History of seizures or head trauma 9. Active or history of major mental illness 10. LFT results 3 times greater than the upper limit of normal at screening. 11. Participants may be excluded if the PI feels they do not meet safety criteria.
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT03215940