RTMS for Treatment of Pain and Craving
CompletedPhase 2NCT03310138
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The purpose of this study is to develop repetitive transcranial magnetic stimulation (rTMS) as a potential treatment for pain in individuals on prescription opioid medication. Repetitive TMS is a non-invasive technique that uses magnetic pulses to temporarily stimulate specific brain areas in awake people (without the need for surgery, anesthetic, or other invasive procedures). This study will test whether 10 days of rTMS over the prefrontal cortex can produce a reduction in perception of pain and the desire to use opiates. TMS has been approved by the FDA as an investigational tool as well a therapy for depression.
Study details
- Official title
- RTMS for Treatment of Pain and Craving
- Conditions
- Pain, Chronic
- Pain Acute
- Interventions
- Device: Real Transcranial Magnetic Stimulation
- Device: Sham Transcranial Magnetic Stimulation
- Sponsor
- Medical University of South Carolina
- Start date
- 2017-07-06
- Primary completion
- 2018-12-12
- Sex
- All
- Age range
- from 18 Years to 65 Years
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * age 18-65 * currently prescribed prescription opiates for pain Exclusion Criteria: * documented history of seizures * unstable chronic medical illness * currently using any medications known to lower seizure risk * metal above the waist * pregnancy * history of a negative reaction to TMS
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT03310138