Achilles Pain Block
CompletedPhase 2, Phase 3NCT03316378
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The purpose of this study is to better understand how the peripheral and central nervous system interact to produce the sensation of pain and motor patterns in patients with achilles tendinopathy (AT). These findings will motivate the development of future clinical studies that incorporate knowledge about pain processing and movement strategies in patients with tendinopathy. Participants with achilles tendinopathy will receive an anesthetic injection to the achilles tendon in order to examine how reduced pain, detected by the peripheral nervous system, alters task performance and perception of pain. We hypothesize that there are factors within the central nervous system that contribute to continued pain and disability in patients with chronic AT.
Study details
- Official title
- Impact of Peripheral Pain Perception on Central Sensitization and Movement Strategies in Patients With Chronic Achilles Tendinopathy
- Conditions
- Achilles Tendon Pain
- Interventions
- Sponsor
- Ruth Chimenti
- Organization
- University of Iowa
- Start date
- 2016-01-28
- Primary completion
- 2018-05-10
- Sex
- All
- Age range
- from 18 Years to 70 Years
- Healthy volunteers
- true
- Results posted
- Yes, on ClinicalTrials.gov
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
For patients with AT Inclusion Criteria: \- Clinical diagnosis of chronic (\>3 months) AT, consisting of pain with pressure at the achilles tendon and report of pain that is aggravated by physical activity Exclusion Criteria: * History of foot or ankle surgery, bilateral lateral epicondyle tendinopathy * Comorbidity that would be aggravated by placing hand in water (Raynaud's, thoracic outlet syndrome) * Comorbidity (e.g. stroke, neurological disorder) that limits ability to participate in exercise * Comorbidity (e.g. rheumatic disease, fibromyalgia) that contributes to pain with activity * Peripheral neuropathy * Previous adverse response to a local anesthetic injection * Are pregnant * Are a ballroom dancer For control participants Inclusion Criteria: \- Sex, Age and BMI-matched to participant with AT Exclusion Criteria: * No history of tendinopathy * No condition that limited activity in the past 6 months * History of foot or ankle surgery, bilateral lateral epicondyle tendinopathy * Comorbidity that would be aggravated by placing hand in water (Raynaud's, thoracic outlet syndrome) * Comorbidity (e.g. stroke, neurological disorder) that limits ability to participate in exercise * Comorbidity (e.g. rheumatic disease, fibromyalgia) that contributes to pain with activity * Peripheral neuropathy * Are pregnant * Are a ballroom dancer
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT03316378