Radial Extracorporeal Shock Wave Therapy for Chronic Non-specific Low Back Pain

Inclusion Criteria: * Adults (both male and female) with non-specific low back pain for more than three months. * Age range: between 18 and 80 years. * Willingness of the patient to participate in the study, and written informed consent signed and personally dated by the patient. * Chronic non-specific low back pain clinically diagnosed as repeated lumbar sourness and swelling pain or a chronic progressive process, accompanied by (i) X-ray examination to exclude lumbar vertebrate fractures, spondylolysis, spondylolisthesis and severe osteoporosis, and/or (ii) MRI with normal signal or low nucleus pulposus signal. * No contraindications for rESWT. Exclusion Criteria: * Children and teenagers below the age of 18. * Elderly aged \>80 years old * No willingness of the patient to participate in the study, and/or written informed consent not signed and not personally dated by the patient. * Previous spinal fracture or spinal surgery. * Protrusion of a lumbar intervertebral disk, ankylosing spondylitis, scoliosis, lumbar spondylolisthesis and lumbar spondylolysis. * Systemic disorders and psychiatric disorders. * Contraindications of C-E drug treatment (treatment of patients allergy to celecoxib, eperisone or sulfonamides, patients with gastrointestinal bleeding or bleeding history, patients with renal dysfunction, patients with severe heart failure, and lactating women). * Contraindications of rESWT ( pregnant patients, patients with blood-clotting disorders \[including local thrombosis\], patients treated with oral anticoagulants, patients with local tumors, patients with local bacterial and/or viral infections \[including lumbar vertebral tuberculosis\], and patients treated with local corticosteroid applications in the time period of six weeks before the first rESWT session \[if applicable\]). * Participation in any other clinical trial in the time period of 12 weeks before potential inclusion in the proposed study.