Mindfulness and Chronic Low Back Pain
CompletedNot applicableNCT03354585
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
The purpose of this study is to see if mindfulness, a form of mental training, or listening to a book alters brain activation in response to raising your leg that may produce the feeling of pain. A technique called functional magnetic resonance imaging (fMRI) allows scientists to determine which parts of the brain are active during a particular task. This study will provide new information about how mindfulness affects the brain.
Study details
- Official title
- Brain Mechanisms Supporting Mindfulness-based Chronic Pain Relief
- Conditions
- Interventions
- Behavioral: mindfulness training
- Behavioral: non-mindfulness training
- Behavioral: book-listening
- Sponsor
- University of California, San Diego
- Start date
- 2020-01-02
- Primary completion
- 2024-02-05
- Sex
- All
- Age range
- from 18 Years to 65 Years
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 2
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion criteria are: * Participants must have a medical evaluation that demonstrates chronic low back pain that is evoked by lifting the legs. Existing medical records, per physician discretion and low back examinations will confirm diagnosis. This will be determined over the phone during the (pre) screening and at study session 1, and will not be contingent on MRI. * Participants must be between the ages of 18-65 years. * Participants must rate their daily chronic pain intensity at a 3 or greater on 0-10 visual analog scale. * Participants must have experienced their radicular pain for at least 3 months duration. * Participants must be right-handed. * Participants must have no prior meditative experience Exclusion criteria: * Participants must not be participating in any new (within 2 weeks prior or anytime after enrollment) pain management procedures during the study period. * Participants must not have had back surgery within the last year before their enrollment into the study. * Participants must not have had any other sensory or motor deficits that precludes participation in this study. * Participants must not have known anomalies of the central nervous system including: stroke, dementia, aneurysm, a personal history of psychosis. * Participants must not have metal implants including ferrous arterial stints or coils, spinal stimulators, pacemakers, or defibrillators, permanently implanted hearing aides, bullets, BBs, or pellets, retinal eye implants, infusion pump for insulin or other medicines, ferrous surgical clips, staples, metal sutures, orthopedic hardware above or including the shoulders, body piercings that cannot be removed. * Participants must not be claustrophobic. * Participants must not produce negative straight leg test (i.e. a test is considered positive when the person reports reproducible pain at 40 degrees of hip flexion or less). * Participants must not be pregnant * Participants must not be over 275 pounds
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT03354585