Reference Values and Clinical Screening Test of Diffuse Noxious Inhibitory Controls (DNIC)
Unknown statusNCT03376867
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Brief summary (from the registry)
Chronic pain (CP) is disabling for people triggering important costs for society. A deficit of diffuse noxious inhibitory controls (DNIC) is one of the CP mechanisms. DNICs are evaluated in research setting using a CPM protocol (conditioned pain modulation). There is a lack of reference values on the effectiveness of DNICs. Wider research on DNIC will help to understand CP and to develop a clinical screening test evaluating DNICs.
Study details
- Official title
- Reference Values of Diffuse Noxious Inhibitory Controls (DNIC) Intensity in a Healthy Adult Population and Develop a Clinical Test to Evaluate DNIC
- Conditions
- Interventions
- Other: Conditioned pain modulation
- Sponsor
- Université de Sherbrooke
- Collaborators
- Canadian Institutes of Health Research (CIHR); Centre for Research of CHUS (CRCHUS); CIHR/SPOR - chronic pain network
- Start date
- 2017-11-27
- Primary completion
- 2022-02-28
- Sex
- All
- Age range
- from 18 Years to 79 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- Canada
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * 18-79 years old * Able to provide consent Exclusion Criteria: * cardiovascular disease (arrhythmia, cerebrovascular accident, infarction...) * Raynaud syndrome * severe psychiatric disease (dementia, schizophrenia, psychosis, major depression) * injuries or loss sensitivity to their forearms or hands * pregnant women or in post-partum period (\<1 year)
Canadian sites (1)
| Facility | City | Province |
|---|---|---|
| Universite de Sherbrooke | Sherbrooke | Quebec |
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT03376867