PET/MRI in the Diagnosis of Chronic Pain
Unknown statusPhase 1NCT03556137
View the official record on ClinicalTrials.gov Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.
This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Several studies have implicated involvement of sigma-1 receptors (SR1s) in the generation of chronic pain, while others are investigating anti SR1 drugs for treatment of chronic pain. Using \[18F\]-FTC-146 and positron emission tomography/magnetic resonance imaging (PET/MRI), the investigators hope to identify the source of pain generation in patients with chronic pain. The purpose of this study is to compare the uptake of \[18F\]FTC-146 in healthy volunteers to that of individuals suffering from chronic pain.
Study details
- Official title
- Use of [18F]FTC-146 PET/MRI in the Diagnosis of Chronic Pain
- Conditions
- Neuropathic Pain
- Nociceptive Pain
- Mixed Pain (Nociceptive and Neuropathic)
- Spinal Pain
- Radiculopathy
- Myelopathy
- Neurogenic Claudication
- Interventions
- Drug: [18F]FTC-146
- Sponsor
- Stanford University
- Collaborators
- GE Healthcare
- Start date
- 2018-07-16
- Primary completion
- 2024-12-31
- Sex
- All
- Age range
- from 18 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- United States
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: Healthy Volunteers: 1. At least 18 years old. 2. Covid Vaccination status: Vaccinated or unvaccinated subjects who received a negative test result from the Covid test within 72 hours of the scan. Pain Patients: 1. At least 18 years old. 2. Chronic pain (nociceptive, neuropathic or mixed pain) lasting greater than 2 months. 3. Pain level of at least 4/10 on a 0-10 Comparative Pain Scale. 4. Covid Vaccination status: Vaccinated or unvaccinated subjects who received a negative test result from the Covid test within 72 hours of the scan. Exclusion Criteria: Healthy Volunteers: 1. Pain 2. Pain Medication 3. MRI incompatible 4. Pregnant or nursing 5. Non-English speaker 6. Claustrophobic Pain Patients: 1. MRI incompatible 2. Pregnant or nursing 3. Non-English speaker 4. Claustrophobic
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT03556137