Quadratus Lumborum in Cesarean Section Trial
CompletedNot applicableNCT03673280
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Postoperative pain of a caesarean section may be of high intensity, especially in the first 48 hours after the procedure, which affects the mother / newborn relationship, in addition to having the potential to progress to chronic pain. The use of intrathecal morphine is effective in post-caesarean analgesia, but carries unwanted side effects, including nausea, vomiting, urinary retention and pruritus. Therefore, alternative techniques of analgesia become necessary. First described in 2007, ultrasound-guided quadratus lumborum (QL) block has gained prominence due to its analgesic superiority to the TAP block. Besides providing somatic analgesia, it also seems to inhibit visceral pain because the local anesthetic reaches the paravertebral space, this was observed by magnetic resonance imaging with contrast medium injected at the QL block site.
Study details
- Official title
- Comparison Between Intrathecal Morphine and Quadratus Lumborum Block for Postpartum Analgesia of Elective Cesareans.
- Conditions
- Postoperative Analgesia
- Interventions
- Procedure: Quadratus Lumborum Block
- Sponsor
- University of Sao Paulo General Hospital
- Start date
- 2018-10-02
- Primary completion
- 2020-02-25
- Sex
- Female
- Age range
- from 18 Years
- Healthy volunteers
- true
- Results posted
- No results posted in this snapshot
- Countries
- Brazil
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Minimum age of 18 years * Minimum gestational age of 37 weeks with a single fetus * Patients scheduled for elective cesarean section through a Pfannenstiel incision under spinal anesthesia * American Society of Anesthesiology physical status (ASA) II * Body mass index (BMI) under 40 kg/m² * No use of opioids for the past 4 weeks * No history of psychotropic drug use * No contraindication for any of the medications involved in the study * No previously known malformations of the fetus * No previous history of chronic pain Exclusion Criteria: * Difficulty in understanding how to use the patient-controlled analgesia (PCA) device * Study protocol violation * Patient decision to withdraw participation
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT03673280