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Aerobic Exercise and Cognitive Training Effects on Postconcussive Symptomology

CompletedNot applicableNCT03674398
View the official record on ClinicalTrials.gov

Recruiting status changes often. Contact the study team listed on ClinicalTrials.gov, and talk to your doctor before joining a study.

This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.

Brief summary (from the registry)

The purpose of this study is to compare a 4-week, moderately intensive, lab and home-based aerobic exercise program versus exercise plus cognitive training. Participants will include individuals who experience lingering symptoms of a head injury or concussion.

Study details

Official title
The Efficacy of an Aerobic Exercise and Cognitive Training Program on Postconcussive Symptomology
Conditions
  • Post-Concussion Syndrome
  • Post-Traumatic Headache
  • Post-Concussive Syndrome, Chronic
  • Head Injury
  • MTBI - Mild Traumatic Brain Injury
  • Acquired Brain Injury
  • Closed Head Injury
Interventions
  • Behavioral: Exercise+CT
  • Behavioral: Exercise only
Sponsor
University of Illinois at Urbana-Champaign
Start date
2018-10-01
Primary completion
2019-05-03
Sex
All
Age range
from 18 Years
Healthy volunteers
true
Results posted
No results posted in this snapshot
Countries
United States
Total sites listed
1

Eligibility criteria

Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * Must have history of at least one concussion (onset was at age 18 or later) * Ability to exercise at moderate to vigorous activity levels (defined as 50%-75% of the adjusted age-predicted maximum heart rate) * Experiencing persistent symptoms (persistent defined as, most days per week for at least 2 weeks since sustaining injury) resulting from concussion or head injury * Access to a smartphone and willingness to allow research staff to install application (and space to allow for installation) * Access to a treadmill to complete exercise outside of lab environment * Willingness to provide proof of concussion or head injury medical diagnosis * Willingness to provide contact information of individual to confirm persistent symptoms if medical diagnosis is unavailable * Willingness to be randomized into one of three groups Exclusion Criteria: * No history of concussion, head injury, or mild traumatic brain injury * Experiencing less than 3 persistent symptoms (persistent defined as, most days per week for at least 2 weeks since sustaining injury) * No access to a smartphone * No access to a treadmill * Too active (as defined by regular exercise most days per week for 30+ minutes over the past 3 months) * Unable or unwilling to comply to lab and home-based exercise prescription * Unable or unwilling to commit to full length of program * Incapable of performing moderately intensive aerobic exercise OR sustaining attention to screen for 20 minutes * Unwilling to be randomized to one of 3 groups * Unable to commute to and from UIUC campus * Already involved in regular weekly physical activity or cognitive training program * Had previously diagnosed mental health condition (e.g., Major Depressive Disorder, Generalized Anxiety Disorder) * Current involvement in litigation specific to injury

Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT03674398