Effect of Safinamide on Parkinson's Disease Related Chronic Pain

Inclusion Criteria: 1. Participant must be 30 years of age or older, at the time of signing the informed consent. 2. Diagnosed with IPD by using the United Kingdom Parkinson's Disease Society Brain Bank criteria for more than 5 years duration. 3. Receiving treatment with a stable dose of oral L-Dopa (including controlled release \[CR\], immediate release \[IR\] or a combination of CR/IR), with and without benserazide/carbidopa, with or without addition of a catechol O-methyltransferase (COMT) inhibitor and may be receiving concomitant treatment with stable doses of a dopamine agonist, an anticholinergic and/or amantadine for at least 4 weeks prior to the randomisation (baseline visit). 4. Hoehn and Yahr stage between 2-3 (inclusive) during the "ON" phase at the screening visit. 5. Experiencing motor fluctuations following optimum titration of treatment medications and within the 4 weeks immediately prior to randomisation. 6. Experiencing chronic pain (i.e. ongoing for ≥3 months prior to screening visit); the Investigator must consider chronic pain directly related to PD and not explained by any other health problem (e.g. peripheral neuropathy, organ disease or arthritis pain) OR consider the intensity of chronic pain specifically aggravated by PD. 7. If taking regular analgesics, the treatment regimen should be stable in the 4 weeks prior to the randomisation visit. 8. Able to maintain an accurate and complete electronic diary with the help of a caregiver. 9. Male or female •A female participant is eligible to participate if she is not pregnant, not breastfeeding, and at least one of the following conditions applies: i.Not a woman of childbearing potential (WOCBP) OR ii.A WOCBP who agrees to follow the contraceptive guidance 10. Capable of giving signed informed consent Exclusion Criteria: 1. Any form of Parkinsonism other than IPD. 2. Diagnosis of chronic migraine (\>15 days per month) or cancer pain. 3. History of bipolar disorder, depression, schizophrenia or other psychotic disorder requiring treatment with neuroleptics. 4. History of dementia or cognitive dysfunction. 5. Severe, peak dose or biphasic dyskinesia. 6. Unpredictable or widely swinging fluctuations. 7. Ophthalmologic history including any of the following conditions: albinism, uveitis, retinitis pigmentosa, retinal degeneration, active retinopathy, severe progressive diabetic retinopathy, inherited retinopathy or family history of hereditary retinal disease. 8. Moderate or severe liver fai…