Photobiomodulation Therapy on Inflammatory Mediators on Low Back Pain
CompletedNot applicableNCT03859505
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This study has no listed site in Canada in this snapshot. It is included as part of the worldwide chronic pain corpus.
Brief summary (from the registry)
Low back pain (LBP) is ranked as one of the most prevalent health conditions. It is likely that some inflammatory mediators could be associated with pain and disability in these patients. Photobiomodulation therapy (PBMT) is a non-pharmacological therapy often used in patients with LBP that decrease release of inflammatory mediators and accelerate muscle repair in different muscle skeletal conditions, as mechanisms of action. The present research project aims to evaluate the effects of PBMT on systemic levels of inflammatory markers and levels of pain intensity in patients with chronic non-specific low back pain.
Study details
- Official title
- Effects of Photobiomodulation Therapy on Inflammatory Mediators in Patients With Chronic Non-specific Low Back Pain: a Randomized Placebo-controlled Trial
- Conditions
- Interventions
- Device: Placebo PBMT
- Device: Active PBMT
- Sponsor
- Universidade Cidade de Sao Paulo
- Collaborators
- Fundação de Amparo à Pesquisa do Estado de São Paulo; University of Bergen
- Start date
- 2019-03-18
- Primary completion
- 2019-03-29
- Sex
- All
- Age range
- from 18 Years to 65 Years
- Results posted
- No results posted in this snapshot
- Countries
- Norway
- Total sites listed
- 1
Eligibility criteria
Show eligibility criteria (verbatim from the registry)
Inclusion Criteria: * patients with chronic non-specific low back pain (defined as pain or discomfort between the costal margins and the inferior gluteal folds, with or without referred symptoms in the lower limbs, for at least 3 month); * with a pain intensity of at least 3 points measured by a 0-10 points pain numerical rating scale; * aged between 18 and 65 years; Exclusion Criteria: * evidence of nerve root compromise (i.e. one or more of motor, reflex or sensation deficit); * serious spinal pathology (such as fracture, tumor, inflammatory and infectious diseases); * serious cardiovascular and metabolic diseases; * previous back surgery; * pregnancy. * severe skin diseases (eg. skin cancer, erysipelas, severe eczema, severe dermatitis, severe psoriasis and severe hives lupus);
Source: ClinicalTrials.gov (US National Library of Medicine), snapshot October 2026. Check the registry for current recruiting status. Record: https://clinicaltrials.gov/study/NCT03859505